{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T05:11:02Z","timestamp":1792300262480,"version":"4.4.0"},"reference-count":15,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,9,28]],"date-time":"2017-09-28T00:00:00Z","timestamp":1506556800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2017,9,28]],"date-time":"2017-09-28T00:00:00Z","timestamp":1506556800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl J Gynecology & Obste"],"published-print":{"date-parts":[[2017,12]]},"abstract":"Abstract<\/jats:title>\n \n Objective<\/jats:title>\n \n To construct reference charts for the fetal middle cerebral artery (\n MCA<\/jats:styled-content>\n ) peak systolic velocity (\n PSV<\/jats:styled-content>\n ,) and the corresponding cord blood hemoglobin values at 24\u201340\u00a0weeks of pregnancy for the identification of fetal anemia.\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n In a cross\u2010sectional study, 300 women with a pregnancy duration of 24\u201340\u00a0weeks planned for delivery within 72\u00a0hours underwent a Doppler study of the\n MCA<\/jats:styled-content>\n and cord blood hemoglobin estimation at delivery. Regression analysis was used to construct reference charts. The validity of the charts was assessed in 40 fetuses from Rhesus\u2010isoimmunized pregnancies.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n The\n MCA PSV<\/jats:styled-content>\n and hemoglobin values increased with advancing gestational age. Multiples of the median (\n MOM<\/jats:styled-content>\n ) were calculated and reference charts were constructed for mild anemia (\n MCA PSV<\/jats:styled-content>\n 1.29\n MOM<\/jats:styled-content>\n ; hemoglobin 0.8\n MOM<\/jats:styled-content>\n ), moderate anemia (\n MCA PSV<\/jats:styled-content>\n 1.50\n MOM<\/jats:styled-content>\n ; hemoglobin 0.6\n MOM<\/jats:styled-content>\n ), and severe anemia (\n MCA PSV<\/jats:styled-content>\n 1.55\n MOM<\/jats:styled-content>\n ; hemoglobin 0.5\n MOM<\/jats:styled-content>\n ). In the validation sample, the hemoglobin value estimated on the basis of the\n MCA PSV<\/jats:styled-content>\n corresponded with the actual hemoglobin range in 90% of the fetuses. The sensitivity was 92% and the specificity was 95%.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n The constructed charts are suitable for the evaluation of fetal anemia in the regional population.<\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/ijgo.12318","type":"journal-article","created":{"date-parts":[[2017,9,5]],"date-time":"2017-09-05T07:09:12Z","timestamp":1504595352000},"page":"307-311","source":"Crossref","is-referenced-by-count":11,"title":["Middle cerebral artery Doppler reference centile charts for the prediction of fetal anemia in a population from India"],"prefix":"10.1002","volume":"139","author":[{"given":"Manisha","family":"Kumar","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Lady Hardinge Medical College New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tarul","family":"Umrawal","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Lady Hardinge Medical College New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anuradha","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Lady Hardinge Medical College New Delhi 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