{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T17:31:18Z","timestamp":1790962278872,"version":"4.1.0"},"reference-count":24,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2018,1,3]],"date-time":"2018-01-03T00:00:00Z","timestamp":1514937600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["R01 CA188428"],"award-info":[{"award-number":["R01 CA188428"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2018,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To determine the effectiveness of community health campaigns (<jats:styled-content style=\"fixed-case\">CHC<\/jats:styled-content>s) as a strategy for human papillomavirus (<jats:styled-content style=\"fixed-case\">HPV<\/jats:styled-content>)\u2010based cervical cancer screening in rural western Kenya.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Between January and November 2016, a cluster\u2010randomized trial was carried out in 12 communities in western Kenya to investigate high\u2010risk <jats:styled-content style=\"fixed-case\">HPV<\/jats:styled-content> testing offered via self\u2010collection to women aged 25\u201365\u00a0years in <jats:styled-content style=\"fixed-case\">CHC<\/jats:styled-content>s versus government health facilities. Outcome measures were the total number of women accessing cervical cancer screening and the proportion of <jats:styled-content style=\"fixed-case\">HPV<\/jats:styled-content>\u2010positive women accessing treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In total, 4944 women underwent <jats:styled-content style=\"fixed-case\">HPV<\/jats:styled-content>\u2010based cervical cancer screening in <jats:styled-content style=\"fixed-case\">CHC<\/jats:styled-content>s (n=2898) or health facilities (n=2046). Screening uptake as a proportion of total eligible women in the population was greater in communities assigned to <jats:styled-content style=\"fixed-case\">CHC<\/jats:styled-content>s (60.0% vs 37.0%, <jats:italic>P<\/jats:italic>&lt;0.001). Rates of treatment acquisition were low in both arms (<jats:styled-content style=\"fixed-case\">CHC<\/jats:styled-content>s 39.2%; health facilities 31.5%; <jats:italic>P<\/jats:italic>=0.408).<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>Cervical cancer screening using <jats:styled-content style=\"fixed-case\">HPV<\/jats:styled-content> testing of self\u2010collected samples reached a larger proportion of women when offered through periodic <jats:styled-content style=\"fixed-case\">CHC<\/jats:styled-content>s compared with health facilities. The community\u2010based model is a promising strategy for cervical cancer prevention. Lessons learned from this trial can be used to identify ways of maximizing the impact of such strategies through greater community participation and improved linkage to treatment.<\/jats:p><jats:p><jats:bold>ClinicalTrials.gov registration<\/jats:bold>: <jats:styled-content style=\"fixed-case\">NCT<\/jats:styled-content>02124252.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ijgo.12415","type":"journal-article","created":{"date-parts":[[2017,12,2]],"date-time":"2017-12-02T07:26:34Z","timestamp":1512199594000},"page":"63-69","source":"Crossref","is-referenced-by-count":67,"title":["Cervical cancer screening through human papillomavirus testing in community health campaigns versus health facilities in rural western Kenya"],"prefix":"10.1002","volume":"141","author":[{"given":"Megan J.","family":"Huchko","sequence":"first","affiliation":[{"name":"Duke Global Health Institute Duke University  Durham NC USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saduma","family":"Ibrahim","sequence":"additional","affiliation":[{"name":"Center for Microbiology Research Kenya Medical Research Institute  Nairobi Kenya"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cinthia","family":"Blat","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Gynecology and Reproductive Sciences University of California  San Francisco CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Craig R.","family":"Cohen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Gynecology and Reproductive Sciences University of California  San Francisco CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer S.","family":"Smith","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics University of North Carolina  Chapel Hill NC USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert A.","family":"Hiatt","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics University of California  San Francisco CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth","family":"Bukusi","sequence":"additional","affiliation":[{"name":"Center for Microbiology Research Kenya Medical Research Institute  Nairobi Kenya"},{"name":"Department of Obstetrics and Gynecology Aga Khan University  Nairobi Kenya"},{"name":"Departments of Global Health and Obstetrics and Gynecology University of Washington  Seattle WA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,1,3]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.25516"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.20107"},{"key":"e_1_2_8_4_1","first-page":"257","article-title":"An overview of cancer survival in Africa, Asia, the Caribbean and Central America: The case for investment in cancer health services","volume":"162","author":"Sankaranarayanan R","year":"2011","journal-title":"IARC Sci Publ"},{"key":"e_1_2_8_5_1","unstructured":"BruniL Barrionuevo\u2010RosasL SerranoB et\u00a0al.Human papillomavirus and related diseases in Kenya. 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