{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T20:05:49Z","timestamp":1762459549004},"reference-count":23,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2018,1,21]],"date-time":"2018-01-21T00:00:00Z","timestamp":1516492800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001826","name":"ZonMw","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001826","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006006","name":"ICIN Netherlands Heart Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006006","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2018,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To determine whether women delivering preterm have unfavorable cardiovascular profiles as compared with women who deliver at term.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A prospective observational cohort study enrolled 165 women with spontaneous preterm delivery (<jats:styled-content style=\"fixed-case\">sPTD<\/jats:styled-content>) at 24<jats:sup>+0<\/jats:sup> and 36<jats:sup>+6<\/jats:sup> gestational weeks in three perinatal care centers in The Netherlands between August 2012 and August 2014. Total cholesterol, triglycerides, high\u2010density lipoprotein (<jats:styled-content style=\"fixed-case\">HDL<\/jats:styled-content>)\u2010cholesterol, low\u2010density lipoprotein (<jats:styled-content style=\"fixed-case\">LDL<\/jats:styled-content>)\u2010cholesterol, apolipoprotein, glucose, and homocysteine were measured within 24\u00a0hours after delivery. Lipids and cardiovascular biochemical risk factors were compared between women with <jats:styled-content style=\"fixed-case\">sPTD<\/jats:styled-content> and an external comparison group of 30 women with term delivery via analysis of covariance.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Mean gestational age at delivery was 30.7\u00a0\u00b1\u00a03.6\u00a0weeks in the <jats:styled-content style=\"fixed-case\">sPTD<\/jats:styled-content> group and 40.3\u00a0\u00b1\u00a01.3\u00a0weeks in the reference group. Data were adjusted for body mass index, age, and center. As compared with the reference group, total cholesterol and <jats:styled-content style=\"fixed-case\">LDL<\/jats:styled-content>\u2010cholesterol levels were lower and glucose levels were higher among women with <jats:styled-content style=\"fixed-case\">sPTD<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>An association between <jats:styled-content style=\"fixed-case\">sPTD<\/jats:styled-content> and unfavorable lipids and cardiovascular biochemical risk factors was not established. The higher levels of glucose in the <jats:styled-content style=\"fixed-case\">sPTD<\/jats:styled-content> group might be due to increased insulin resistance, which is associated with a higher risk of <jats:styled-content style=\"fixed-case\">sPTD<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ijgo.12423","type":"journal-article","created":{"date-parts":[[2017,12,7]],"date-time":"2017-12-07T16:46:59Z","timestamp":1512665219000},"page":"206-211","source":"Crossref","is-referenced-by-count":5,"title":["Cardiovascular biochemical risk factors among women with spontaneous preterm delivery"],"prefix":"10.1002","volume":"141","author":[{"given":"Karst Y.","family":"Heida","sequence":"first","affiliation":[{"name":"Division of Woman and Baby Department of Obstetrics University Medical Center Utrecht  Utrecht Netherlands"},{"name":"Julius Center for Health Sciences and Primary Care University Medical Center Utrecht  Utrecht 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