{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T16:35:40Z","timestamp":1775147740591,"version":"3.50.1"},"reference-count":14,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2018,4,10]],"date-time":"2018-04-10T00:00:00Z","timestamp":1523318400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology & Obste"],"published-print":{"date-parts":[[2018,7]]},"abstract":"Abstract<\/jats:title>Background<\/jats:title>Observational studies have reported varying results about the association of velamentous cord insertion (VCI<\/jats:styled-content>) with adverse pregnancy outcomes.<\/jats:p><\/jats:sec>Objectives<\/jats:title>To evaluate the risk of preterm delivery among singleton pregnancies complicated by VCI<\/jats:styled-content>.<\/jats:p><\/jats:sec>Search strategy<\/jats:title>Various databases were searched for English\u2010language articles published up to February, 28, 2017, using keywords including VCI<\/jats:styled-content>; abnormal placentation; abnormal cord insertions; adverse perinatal outcomes; and preterm birth. Outcome measures included preterm delivery; pre\u2010eclampsia; cesarean delivery; fetal demise in utero (FDIU<\/jats:styled-content>); and small for gestational age (SGA<\/jats:styled-content>).<\/jats:p><\/jats:sec>Selection criteria<\/jats:title>Only studies involving VCI<\/jats:styled-content> were included in the meta\u2010analysis.<\/jats:p><\/jats:sec>Data collection and analysis<\/jats:title>Analyses were performed using RevMan version 5.3.5 (The Nordic Cochrane Centre, Copenhagen, Denmark).<\/jats:p><\/jats:sec>Main results<\/jats:title>There were six studies included in the analysis. The VCI<\/jats:styled-content> and control groups comprised 16\u00a0295 and 1\u00a0366\u00a0485 women, respectively. An increased incidence of preterm delivery was found for the VCI<\/jats:styled-content> group compared with the control group (11.8% vs 7.0%; adjusted odds ratio [aOR<\/jats:styled-content>] 1.95, 95% confidence interval [CI<\/jats:styled-content>] 1.85\u20132.04). A diagnosis of VCI<\/jats:styled-content> was also associated with cesarean delivery (aOR<\/jats:styled-content> 1.17, 95% CI<\/jats:styled-content> 1.12\u20131.23), SGA<\/jats:styled-content> (aOR<\/jats:styled-content> 1.93, 95% CI<\/jats:styled-content> 1.83\u20132.04), and FDIU<\/jats:styled-content> (aOR<\/jats:styled-content> 3.96, 95% CI<\/jats:styled-content> 3.21\u20134.89).<\/jats:p><\/jats:sec>Conclusion<\/jats:title>The presence of VCI was associated with adverse pregnancy outcomes.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ijgo.12489","type":"journal-article","created":{"date-parts":[[2018,3,24]],"date-time":"2018-03-24T02:34:31Z","timestamp":1521858871000},"page":"9-14","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":34,"title":["A systematic review and meta\u2010analysis of velamentous cord insertion among singleton pregnancies and the risk of preterm delivery"],"prefix":"10.1002","volume":"142","author":[{"given":"Samantha","family":"de los Reyes","sequence":"first","affiliation":[{"name":"Department of Gynecology and Obstetrics Johns Hopkins University School of Medicine Baltimore MD USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janice","family":"Henderson","sequence":"additional","affiliation":[{"name":"Division of Maternal Fetal Medicine Department of Gynecology and Obstetrics Johns Hopkins University School of Medicine Baltimore MD USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahizechukwu C.","family":"Eke","sequence":"additional","affiliation":[{"name":"Division of Maternal Fetal Medicine Department of Gynecology and Obstetrics Johns Hopkins University School of Medicine Baltimore MD USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,4,10]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-994684"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-23941-0_5"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1028-4559(09)60185-6"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(14)61698-6"},{"key":"e_1_2_7_6_1","first-page":"S78","article-title":"Placental implantation abnormalities and risk of preterm delivery: A systematic review and metaanalysis","volume":"213","author":"Vahanian SA","year":"2015","journal-title":"Obstet Gynecol"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2012.08.021"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.3109\/14767058.2014.918098"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/aogs.13035"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-015-3912-x"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0070380"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/0029-7844(95)00339-8"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.283.15.2008"},{"key":"e_1_2_7_14_1","unstructured":"DeeksJ HigginsJ AltmanD GreenS.Cochrane handbook for systematic reviews of interventions version 5.1. 0. 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Accessed February 10 2017."},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/sim.1186"}],"container-title":["International Journal of Gynecology & Obstetrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fijgo.12489","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijgo.12489","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T12:23:40Z","timestamp":1695471820000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/ijgo.12489"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4,10]]},"references-count":14,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,7]]}},"alternative-id":["10.1002\/ijgo.12489"],"URL":"https:\/\/doi.org\/10.1002\/ijgo.12489","archive":["Portico"],"relation":{},"ISSN":["0020-7292","1879-3479"],"issn-type":[{"value":"0020-7292","type":"print"},{"value":"1879-3479","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,4,10]]},"assertion":[{"value":"2017-08-29","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-03-16","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-04-10","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}