{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T19:13:35Z","timestamp":1791832415311,"version":"4.3.4"},"reference-count":20,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2018,4,9]],"date-time":"2018-04-09T00:00:00Z","timestamp":1523232000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology & Obste"],"published-print":{"date-parts":[[2018,7]]},"abstract":"Abstract<\/jats:title>Objective<\/jats:title>To describe maternal and perinatal outcomes among pregnant women with suspected Ebola virus disease (EVD<\/jats:styled-content>) in Sierra Leone.<\/jats:p><\/jats:sec>Methods<\/jats:title>Observational investigation of maternal and perinatal outcomes among pregnant women with suspected EVD<\/jats:styled-content> from five districts in Sierra Leone from June to December 2014. Suspected cases were ill pregnant women with symptoms suggestive of EVD<\/jats:styled-content> or relevant exposures who were tested for EVD<\/jats:styled-content>. Case frequencies and odds ratios were calculated to compare patient characteristics and outcomes by EVD<\/jats:styled-content> status.<\/jats:p><\/jats:sec>Results<\/jats:title>There were 192 suspected cases: 67 (34.9%) EVD<\/jats:styled-content>\u2010positive, 118 (61.5%) EVD<\/jats:styled-content>\u2010negative, and 7 (3.6%) EVD<\/jats:styled-content> status unknown. Women with EVD<\/jats:styled-content> had increased odds of death (OR<\/jats:styled-content> 10.22; 95% CI<\/jats:styled-content>, 4.87\u201321.46) and spontaneous abortion (OR<\/jats:styled-content> 4.93; 95% CI<\/jats:styled-content>, 1.79\u201313.55) compared with those without EVD<\/jats:styled-content>. Women without EVD<\/jats:styled-content> had a high frequency of death (30.2%) and stillbirths (65.9%). One of 14 neonates born following EVD<\/jats:styled-content>\u2010negative and five of six neonates born following EVD<\/jats:styled-content>\u2010positive pregnancies died.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>EVD<\/jats:styled-content>\u2010positive and EVD<\/jats:styled-content>\u2010negative women with suspected EVD<\/jats:styled-content> had poor outcomes, highlighting the need for increased attention and resources focused on maternal and perinatal health during an urgent public health response. Capturing pregnancy status in nationwide surveillance of EVD<\/jats:styled-content> can help improve understanding of disease burden and design effective interventions.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ijgo.12490","type":"journal-article","created":{"date-parts":[[2018,3,23]],"date-time":"2018-03-23T08:46:48Z","timestamp":1521794808000},"page":"71-77","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Maternal and perinatal outcomes in pregnant women with suspected Ebola virus disease in Sierra Leone, 2014"],"prefix":"10.1002","volume":"142","author":[{"given":"Meghan","family":"Lyman","sequence":"first","affiliation":[{"name":"Epidemic Intelligence Service Center for Surveillance, Epidemiology and Laboratory Service Centers for Disease Control and Prevention Atlanta GA USA"},{"name":"Division of Healthcare Quality Promotion National Center for Emerging and Zoonotic Infectious Diseases Centers for Disease Control and Prevention Atlanta GA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonetta Johnson","family":"Mpofu","sequence":"additional","affiliation":[{"name":"Division of Reproductive Health National Center for Chronic Disease Prevention and Health Promotion Centers for Disease Control and Prevention Atlanta GA USA"},{"name":"US Public Health Service Commissioned Corps Rockville MD USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatma","family":"Soud","sequence":"additional","affiliation":[{"name":"Prevention Care and Treatment Branch Centers for Disease Control and Prevention, c\/o American Embassy Lusaka Zambia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Titilope","family":"Oduyebo","sequence":"additional","affiliation":[{"name":"Epidemic Intelligence Service Center for Surveillance, Epidemiology and Laboratory Service Centers for Disease Control and Prevention Atlanta GA USA"},{"name":"Division of Reproductive Health National Center for Chronic Disease Prevention and Health Promotion Centers for Disease Control and Prevention Atlanta GA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sascha","family":"Ellington","sequence":"additional","affiliation":[{"name":"Division of Reproductive Health National Center for Chronic Disease Prevention and Health Promotion Centers for Disease Control and Prevention Atlanta GA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriel W.","family":"Schlough","sequence":"additional","affiliation":[{"name":"West African Medical Missions Inc Freetown Sierra Leone"},{"name":"Partners in Health Freetown Sierra Leone"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alimamy P.","family":"Koroma","sequence":"additional","affiliation":[{"name":"Ministry of Health and Sanitation Freetown Sierra Leone"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jevon","family":"McFadden","sequence":"additional","affiliation":[{"name":"Division of State and Local Readiness Centers for Disease Control and Prevention assigned to the Michigan department of Community Health Lansing MI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diane","family":"Morof","sequence":"additional","affiliation":[{"name":"Division of Reproductive Health National Center for Chronic Disease Prevention and Health Promotion Centers for Disease Control and Prevention Atlanta GA USA"},{"name":"US Public Health Service Commissioned Corps Rockville MD USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,4,9]]},"reference":[{"key":"e_1_2_8_2_1","unstructured":"World Health Organization.Ebola viral disease: fact sheet. 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