{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T23:36:54Z","timestamp":1773790614023,"version":"3.50.1"},"reference-count":29,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2018,4,24]],"date-time":"2018-04-24T00:00:00Z","timestamp":1524528000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2018,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To assess adverse events following surgical repair of pelvic organ prolapse (<jats:styled-content style=\"fixed-case\">POP<\/jats:styled-content>) with or without the use of transvaginal mesh.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The present retrospective study was conducted among women who underwent surgical <jats:styled-content style=\"fixed-case\">POP<\/jats:styled-content> repair at Soroka University Medical Center, Beer Sheva, Israel, between January 1, 2013, and December 31, 2015. Patients underwent anterior and posterior colporrhaphy either with transvaginal mesh (Elevate Prolapse Repair System; American Medical Systems, Minnetonka, <jats:styled-content style=\"fixed-case\">MN<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> USA<\/jats:styled-content>) or without transvaginal mesh (native tissue repair). Perioperative adverse events were assessed using the Clavien\u2010Dindo classification; multivariate regression models were constructed to predict minor and major adverse events.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were 111 women included; 35 were treated with transvaginal mesh, and 76 underwent native tissue repair. Women undergoing native tissue repair had a lower mean grade of cystocele (<jats:italic>P<\/jats:italic>=0.023) and a higher rate of urinary stress incontinence (<jats:italic>P<\/jats:italic>=0.017) than patients treated with transvaginal mesh. The duration of surgery (<jats:italic>P<\/jats:italic>=0.002), duration of hospitalization (<jats:italic>P<\/jats:italic>&lt;0.001), and the amount of blood loss (<jats:italic>P<\/jats:italic>=0.021) were lower in the native tissue repair group. Repair with transvaginal mesh was not associated with increased odds of major or minor adverse events (<jats:italic>P<\/jats:italic>&gt;0.05 for all models examined).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Perioperative and postoperative adverse events were comparable regardless of the operative approach.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ijgo.12501","type":"journal-article","created":{"date-parts":[[2018,4,10]],"date-time":"2018-04-10T08:11:00Z","timestamp":1523347860000},"page":"108-113","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Comparative analysis of early adverse events of pelvic organ prolapse repair with or without transvaginal mesh using Clavien\u2010Dindo classification"],"prefix":"10.1002","volume":"142","author":[{"given":"Limor","family":"Besser","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Soroka University Medical Center Faculty of Health Sciences Ben\u2010Gurion University of the Negev  Beer Sheva Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Polina","family":"Schwarzman","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Soroka University Medical Center Faculty of Health Sciences Ben\u2010Gurion University of the Negev  Beer Sheva Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Salvatore A.","family":"Mastrolia","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Soroka University Medical Center Faculty of Health Sciences Ben\u2010Gurion University of the Negev  Beer Sheva Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reut","family":"Rotem","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Shaare Zedek Medical Center Hebrew University Medical School  Jerusalem 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