{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T18:41:44Z","timestamp":1768416104986,"version":"3.49.0"},"reference-count":25,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2018,6,15]],"date-time":"2018-06-15T00:00:00Z","timestamp":1529020800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100002799","name":"Capital Medical University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002799","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology & Obste"],"published-print":{"date-parts":[[2018,9]]},"abstract":"Abstract<\/jats:title>Objective<\/jats:title>To examine the relationship between combination antiretroviral therapy (cART<\/jats:styled-content>) and preterm delivery (PTD<\/jats:styled-content>) or low delivery weight among pregnant Chinese women with HIV<\/jats:styled-content>.<\/jats:p><\/jats:sec>Methods<\/jats:title>The present retrospective cross\u2010sectional medical chart review enrolled pregnant women with HIV<\/jats:styled-content> who delivered at five tertiary hospitals in China between January 1, 2009, and December 31, 2014. Generalized linear mixed modeling was used to explore PTD<\/jats:styled-content> (<37\u00a0weeks of pregnancy) and low delivery weight (<2500\u00a0g) risk factors.<\/jats:p><\/jats:sec>Results<\/jats:title>Among 731 mother\u2013neonate pairs, 93 (12.7%) mothers had PTD<\/jats:styled-content> and 133 (18.2%) neonates had low delivery weight. Use of cART<\/jats:styled-content> pre\u2010conception or its initiation in the first trimester was associated with PTD<\/jats:styled-content> (adjusted odds ratio [aOR<\/jats:styled-content>] 2.82; P<\/jats:italic>=0.002) and low delivery weight (aOR<\/jats:styled-content> 1.92; P<\/jats:italic>=0.026). First\u2010trimester cART<\/jats:styled-content> initiation was associated with PTD<\/jats:styled-content> for lopinavir\/ritonavir (aOR<\/jats:styled-content> 2.59; P<\/jats:italic>=0.006) and nevirapine (aOR<\/jats:styled-content>, 2.64; P<\/jats:italic>=0.003) regimens compared with later; the same was not true for efavirenz\u2010based cART<\/jats:styled-content> (P<\/jats:italic>=0.197). Low maternal body mass index (\u226423.5) before delivery was independently associated with an increased likelihood of low delivery weight (aOR<\/jats:styled-content> 1.60; P<\/jats:italic>=0.038) but not PTD.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>Early use of cART<\/jats:styled-content> was associated with increased likelihood of PTD<\/jats:styled-content> and low delivery weight. Efavirenz\u2010based cART<\/jats:styled-content> appeared to be favorable for women with HIV<\/jats:styled-content> regardless of the timing of cART<\/jats:styled-content> initiation. Good nutritional status is essential to prevent low delivery weight.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ijgo.12532","type":"journal-article","created":{"date-parts":[[2018,5,17]],"date-time":"2018-05-17T19:58:57Z","timestamp":1526587137000},"page":"300-307","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Risk factors associated with preterm delivery and low delivery weight among HIV<\/scp>\u2010exposed neonates in China"],"prefix":"10.1002","volume":"142","author":[{"given":"Liming","family":"Wang","sequence":"first","affiliation":[{"name":"Beijing Ditan Hospital Capital Medical University Beijing China"},{"name":"Clinical Center for HIV\/AIDS Capital Medical University Beijing China"},{"name":"Division of Global HIV\/TB\u2013China Office US Centers for Disease Control and Prevention Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongxin","family":"Zhao","sequence":"additional","affiliation":[{"name":"Beijing Ditan Hospital Capital Medical University Beijing China"},{"name":"Clinical Center for HIV\/AIDS Capital Medical University Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weiping","family":"Cai","sequence":"additional","affiliation":[{"name":"Guangzhou No. 8 People's Hospital Guangdong China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jie","family":"Tao","sequence":"additional","affiliation":[{"name":"Liuzhou Maternal and Child Health Hospital Guangxi China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qingxia","family":"Zhao","sequence":"additional","affiliation":[{"name":"Zhengzhou No. 6 People's Hospital Henan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lijun","family":"Sun","sequence":"additional","affiliation":[{"name":"Beijing You'an Hospital Capital Medical University Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qingbo","family":"Fan","sequence":"additional","affiliation":[{"name":"Peking Union Medical College Hospital Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Athena P.","family":"Kourtis","sequence":"additional","affiliation":[{"name":"Division of Reproductive Health US Centers for Disease Control and Prevention Atlanta GA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Colin","family":"Shepard","sequence":"additional","affiliation":[{"name":"Division of Global HIV\/TB\u2013China Office US Centers for Disease Control and Prevention Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fujie","family":"Zhang","sequence":"additional","affiliation":[{"name":"Beijing Ditan Hospital Capital Medical University Beijing China"},{"name":"Clinical Center for HIV\/AIDS Capital Medical University Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,6,15]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0911486"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1293.2010.00876.x"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cis198"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/00002030-200411190-00019"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.aids.0000253362.01696.9d"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa991159"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jis728"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0b013e32802ef2f6"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2010.02689.x"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198501103120204"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(02)11476-0"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jis553"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(10)70288-7"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0b013e32830b8ab9"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiv389"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1136\/sti.2008.032300"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1186\/1758-2652-14-42"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2014.06.018"},{"key":"e_1_2_8_20_1","unstructured":"China Health Statistics Yearbooks.National Health and Family Planning Commission of the People's Republic of China. Access at\u00a0http:\/\/www.nhfpc.gov.cn\/zwgk\/tjnj1\/ejlist.shtml. Accessed June 21 2017."},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAI.0000000000000909"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiv390"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-3018(16)30195-3"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12978-016-0149-5"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/87.6.1639"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1079\/PHN2001251"}],"container-title":["International Journal of Gynecology & Obstetrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fijgo.12532","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijgo.12532","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,18]],"date-time":"2023-09-18T11:11:47Z","timestamp":1695035507000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/ijgo.12532"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,6,15]]},"references-count":25,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2018,9]]}},"alternative-id":["10.1002\/ijgo.12532"],"URL":"https:\/\/doi.org\/10.1002\/ijgo.12532","archive":["Portico"],"relation":{},"ISSN":["0020-7292","1879-3479"],"issn-type":[{"value":"0020-7292","type":"print"},{"value":"1879-3479","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,6,15]]},"assertion":[{"value":"2017-11-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-05-15","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-06-15","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}