{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T10:59:21Z","timestamp":1773831561026,"version":"3.50.1"},"reference-count":20,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2018,9,6]],"date-time":"2018-09-06T00:00:00Z","timestamp":1536192000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2018,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To compare the efficacy of transcervical resection of the cervix (<jats:styled-content style=\"fixed-case\">TCRC<\/jats:styled-content>) and loop electrosurgical excision procedure (<jats:styled-content style=\"fixed-case\">LEEP<\/jats:styled-content>) in the treatment of high\u2010grade cervical squamous intraepithelial lesions (<jats:styled-content style=\"fixed-case\">HSIL<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective case record review was conducted of patients with <jats:styled-content style=\"fixed-case\">HSIL<\/jats:styled-content> treated with <jats:styled-content style=\"fixed-case\">TCRC<\/jats:styled-content> or <jats:styled-content style=\"fixed-case\">LEEP<\/jats:styled-content> at Guangdong General Hospital, Guangdong Academy of Medical Sciences and Zhujiang Hospital, Guangzhou, China, from 2009 to 2015. The clinical characteristics, cone margin statuses, clinical outcomes, and adverse events were compared between the two groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among 647 included patients, 292 (45.1%) were treated with <jats:styled-content style=\"fixed-case\">TCRC<\/jats:styled-content> and 355 (54.9%) with <jats:styled-content style=\"fixed-case\">LEEP<\/jats:styled-content>. The incidences of positive margins, persistent and recurrent lesions, and intraoperative bleeding were lower in the <jats:styled-content style=\"fixed-case\">TCRC<\/jats:styled-content> group than in the <jats:styled-content style=\"fixed-case\">LEEP<\/jats:styled-content> group (<jats:italic>P<\/jats:italic>&lt;0.001 for all comparisons). The rates of cervical adhesions were comparable between the two groups. During <jats:styled-content style=\"fixed-case\">TCRC<\/jats:styled-content>, 78 (26.7%) intrauterine lesions were diagnosed; most of these had been missed by transvaginal sonography.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">TCRC<\/jats:styled-content> may be an alternative method to <jats:styled-content style=\"fixed-case\">LEEP<\/jats:styled-content> in the treatment of <jats:styled-content style=\"fixed-case\">HSIL<\/jats:styled-content>. Compared with <jats:styled-content style=\"fixed-case\">LEEP<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> TCRC<\/jats:styled-content> has comparable clinical efficacy without additional adverse events. Moreover, <jats:styled-content style=\"fixed-case\">TCRC<\/jats:styled-content> is useful for detecting and\/or removing intrauterine lesions during surgery.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ijgo.12655","type":"journal-article","created":{"date-parts":[[2018,8,22]],"date-time":"2018-08-22T15:11:55Z","timestamp":1534950715000},"page":"306-312","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Comparative analysis of transcervical resection and loop electrosurgical excision in the treatment of high\u2010grade cervical intraepithelial neoplasia"],"prefix":"10.1002","volume":"143","author":[{"given":"Meizhuang","family":"Chen","sequence":"first","affiliation":[{"name":"The Second School of Clinical Medicine Southern Medical University  Guangzhou China"},{"name":"Department of Obstetrics and Gynecology Guangdong General Hospital Guangdong Academy of Medical Sciences  Guangzhou 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