{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T20:19:18Z","timestamp":1779913158962,"version":"3.53.1"},"reference-count":23,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2018,11,26]],"date-time":"2018-11-26T00:00:00Z","timestamp":1543190400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Research and Clinical Center for Infertility"},{"name":"Yazd Reproductive Sciences Institute"},{"DOI":"10.13039\/501100015034","name":"Shahid Sadoughi University of Medical Sciences","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100015034","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2019,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To explore assisted reproductive outcomes among women with different polycystic ovary syndrome (<jats:styled-content style=\"fixed-case\">PCOS<\/jats:styled-content>) phenotypes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective cohort study included women with <jats:styled-content style=\"fixed-case\">PCOS<\/jats:styled-content> who were treated at Yazd Research and Clinical Center for Infertility, Yazd, Iran, using the Gn<jats:styled-content style=\"fixed-case\">RH<\/jats:styled-content> antagonist protocol between April 1, 2015, and August 31, 2017. Clinical pregnancy was the primary outcome, and chemical pregnancy, implantation rate, fertilization rate, and spontaneous abortion rate, were the secondary outcomes that were evaluated among four defined phenotypes of women with <jats:styled-content style=\"fixed-case\">PCOS<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Significant differences were observed between the phenotypes for the levels of luteinizing hormone, anti\u2010M\u00fcllerian hormone, fasting blood sugar, and total testosterone concentration; similarly, the percentage of women with luteinizing hormone\/follicle stimulating hormone ratio of at least 2.5 differed between <jats:styled-content style=\"fixed-case\">PCOS<\/jats:styled-content> phenotypes (all <jats:italic>P<\/jats:italic>&lt;0.001). There were also significant differences in estradiol level (<jats:italic>P<\/jats:italic>&lt;0.001) and the number of matured follicles (<jats:italic>P<\/jats:italic>=0.002) between different phenotypes. No significant differences were observed in the fertilization and implantation rates, as well as chemical and clinical pregnancy rates (all <jats:italic>P<\/jats:italic>&gt;0.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>No significant differences were observed in assisted reproductive technique outcome among women with different phenotypes of <jats:styled-content style=\"fixed-case\">PCOS<\/jats:styled-content> undergoing frozen\u2010thawed embryo transfer.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ijgo.12707","type":"journal-article","created":{"date-parts":[[2018,11,9]],"date-time":"2018-11-09T07:49:50Z","timestamp":1541749790000},"page":"147-152","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Assisted reproductive outcomes in women with different polycystic ovary syndrome phenotypes"],"prefix":"10.1002","volume":"144","author":[{"given":"Maryam","family":"Eftekhar","sequence":"first","affiliation":[{"name":"Research and Clinical Center for Infertility Yazd Reproductive Sciences Institute Shahid Sadoughi University of Medical Sciences  Yazd Iran"},{"name":"Research Abortion Center Yazd Reproductive Sciences Institute Shahid Sadoughi University of Medical Sciences  Yazd Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elham S.","family":"Mirhashemi","sequence":"additional","affiliation":[{"name":"Research and Clinical Center for Infertility Yazd Reproductive Sciences Institute Shahid Sadoughi University of Medical Sciences  Yazd Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nasim","family":"Tabibnejad","sequence":"additional","affiliation":[{"name":"Research and Clinical Center for Infertility Yazd Reproductive Sciences Institute Shahid Sadoughi University of Medical Sciences  Yazd Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,11,26]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-015-3889-5"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.19082\/5820"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.2147\/CLEP.S37559"},{"key":"e_1_2_8_5_1","volume-title":"Textbook of Assisted Reproductive Techniques: Volume 2: Clinical Perspectives","author":"Gardner DK","year":"2017"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13104-018-3207-y"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0043-121264"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1080\/09513590.2017.1412429"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2003.10.004"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(97)81391-X"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.4274\/tjod.90094"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2006.03.046"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10815-013-0145-4"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(16)61034-8"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rbmo.2016.01.010"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmw027"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI2081"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/15.12.2471"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.GME.0000123642.76105.6E"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmq034"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10815-011-9627-4"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.29252\/ijrm.14.8.507"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2008.08.127"},{"key":"e_1_2_8_24_1","first-page":"715","article-title":"Anti\u2010mullerian hormone as a predictive factor in assisted reproductive technique of polycystic ovary syndrome patients","volume":"49","author":"Aleyasin A","year":"2011","journal-title":"Acta Medica Iranica"}],"container-title":["International Journal of Gynecology &amp; 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