{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T13:28:48Z","timestamp":1770816528802,"version":"3.50.1"},"reference-count":19,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2018,12,10]],"date-time":"2018-12-10T00:00:00Z","timestamp":1544400000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000061","name":"Fogarty International Center","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000061","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["D43TW010543"],"award-info":[{"award-number":["D43TW010543"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2019,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To determine the association between low maternal vitamin D levels and preterm delivery among parturients in Lagos, Nigeria.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The present study was an analytical cross\u2010sectional study of women with preterm deliveries (defined as &lt;37\u00a0weeks) and women with term deliveries (defined as \u226537\u00a0weeks) at the labor unit of Lagos University Teaching Hospital between December 1, 2015, and October 31, 2016. Relevant information was obtained via a proforma, and maternal venous samples were collected immediately after delivery. Serum 25\u2010hydroxy vitamin D was determined by a vitamin D enzyme\u2010linked immunoassay kit.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The study enrolled 103 women in each group. The overall prevalence of vitamin D deficiency was 14.1% (29\/206). 24 (23.3%) women with preterm delivery had low serum vitamin D (&lt;30\u00a0ng\/<jats:styled-content style=\"fixed-case\">mL<\/jats:styled-content>) as compared with only 5 (4.9%) women with term delivery (<jats:italic>P<\/jats:italic>&lt;0.001). Compared with normal serum vitamin D levels, low maternal vitamin D had an approximately nine\u2010fold higher likelihood of preterm delivery (adjusted odds ratio 9.41, 95% confidence interval 2.42\u201336.54; <jats:italic>P<\/jats:italic>&lt;0.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The prevalence of serum vitamin D deficiency was higher among women with preterm delivery than among those with term delivery. The potential role of prenatal vitamin D supplementation in the prevention of preterm delivery should be further investigated.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ijgo.12719","type":"journal-article","created":{"date-parts":[[2018,11,21]],"date-time":"2018-11-21T13:39:28Z","timestamp":1542807568000},"page":"216-220","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Maternal serum vitamin D levels and preterm delivery among low\u2010risk parturients in Lagos, Nigeria"],"prefix":"10.1002","volume":"144","author":[{"given":"Ayodeji A.","family":"Oluwole","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynaecology College of medicine University of Lagos  Lagos Nigeria"},{"name":"Department of Obstetrics and Gynaecology Lagos University Teaching Hospital  Idi\u2010Araba, Lagos Nigeria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kehinde S.","family":"Okunade","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology College of medicine University of Lagos  Lagos Nigeria"},{"name":"Department of Obstetrics and Gynaecology Lagos University Teaching Hospital  Idi\u2010Araba, Lagos Nigeria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Osemen E.","family":"Okojie","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology Lagos University Teaching Hospital  Idi\u2010Araba, Lagos Nigeria"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,12,10]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu2040408"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu5010111"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.3003045"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(12)60820-4"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)31593-8"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/412831"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu8050301"},{"key":"e_1_2_8_9_1","first-page":"1459","article-title":"High prevalence of maternal vitamin D deficiency in preterm birth in Northeast China, Shenyang","volume":"8","author":"Zhu T","year":"2015","journal-title":"Int J Clin Exp Pathol"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/137.2.447"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.4103\/0300-1652.140381"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1080\/01443615.2016.1196483"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0123763"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1177\/1933719113493513"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.4103\/2249-4847.194164"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2009-2158"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/80.6.1689S"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/80.6.1678S"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsbmb.2014.11.013"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.12659\/MSM.898117"}],"container-title":["International Journal of Gynecology &amp; 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