{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T04:29:15Z","timestamp":1783052955725,"version":"3.54.6"},"reference-count":21,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2019,2,14]],"date-time":"2019-02-14T00:00:00Z","timestamp":1550102400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2019,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To examine Ebola virus disease (<jats:styled-content style=\"fixed-case\">EVD<\/jats:styled-content>) symptom prevalence and <jats:styled-content style=\"fixed-case\">EVD<\/jats:styled-content> status among pregnant women in Ebola isolation units in Sierra Leone.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In an observational study, data were obtained for pregnant women admitted to Ebola isolation units across four districts in Sierra Leone from June 29, 2014, to December 20, 2014. Women were admitted to isolation units if they had suspected <jats:styled-content style=\"fixed-case\">EVD<\/jats:styled-content> exposures or fever (temperature &gt;38\u00b0C) and three or more self\u2010reported symptoms suggestive of <jats:styled-content style=\"fixed-case\">EVD<\/jats:styled-content>. Associations were examined between <jats:styled-content style=\"fixed-case\">EVD<\/jats:styled-content> status and each symptom using \u03c7<jats:sup>2<\/jats:sup> tests and logistic regression adjusting for age\/labor status.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 176 pregnant women isolated, 55 (32.5%) tested positive for <jats:styled-content style=\"fixed-case\">EVD<\/jats:styled-content>. Using logistic regression models adjusted for age, <jats:styled-content style=\"fixed-case\">EVD<\/jats:styled-content>\u2010positive women were significantly more likely to have fever, self\u2010reported fatigue\/weakness, nausea\/vomiting, headache, muscle\/joint pain, chest pain, vaginal bleeding, unexplained bleeding, or sore throat upon admission. In models adjusted for age\/labor, only women with fever or vaginal bleeding upon admission were significantly more likely to be <jats:styled-content style=\"fixed-case\">EVD<\/jats:styled-content>\u2010positive.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Several <jats:styled-content style=\"fixed-case\">EVD<\/jats:styled-content> symptoms and complications increased the odds of testing <jats:styled-content style=\"fixed-case\">EVD<\/jats:styled-content>\u2010positive; some of these were also signs and symptoms of labor\/pregnancy complications. The study results highlight the need to refine screening for pregnant women with <jats:styled-content style=\"fixed-case\">EVD<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ijgo.12775","type":"journal-article","created":{"date-parts":[[2019,2,1]],"date-time":"2019-02-01T11:00:08Z","timestamp":1549018808000},"page":"76-82","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Clinical presentation of pregnant women in isolation units for Ebola virus disease in Sierra Leone, 2014"],"prefix":"10.1002","volume":"145","author":[{"given":"Jonetta J.","family":"Mpofu","sequence":"first","affiliation":[{"name":"Division of Reproductive Health National Center for Chronic Disease Prevention and Health Promotion Centers for Disease Control and Prevention  Atlanta GA USA"},{"name":"US Public Health Service Commissioned Corps  Rockville MD USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatma","family":"Soud","sequence":"additional","affiliation":[{"name":"Zambia Country Office Centers for Disease Control and Prevention  Lusaka Zambia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meghan","family":"Lyman","sequence":"additional","affiliation":[{"name":"Epidemic Intelligence Service Division of Scientific Education and Professional Development Office of Public Health Scientific Services Centers for Disease Control and Prevention  Atlanta GA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alimamy P.","family":"Koroma","sequence":"additional","affiliation":[{"name":"Ministry of Health and Sanitation  Freetown Sierra Leone"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diane","family":"Morof","sequence":"additional","affiliation":[{"name":"Division of Reproductive Health National Center for Chronic Disease Prevention and Health Promotion Centers for Disease Control and Prevention  Atlanta GA USA"},{"name":"US Public Health Service Commissioned Corps  Rockville MD USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sascha","family":"Ellington","sequence":"additional","affiliation":[{"name":"Division of Reproductive Health National Center for Chronic Disease Prevention and Health Promotion Centers for Disease Control and Prevention  Atlanta GA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samuel S.","family":"Kargbo","sequence":"additional","affiliation":[{"name":"Ministry of Health and Sanitation  Freetown Sierra Leone"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William","family":"Callaghan","sequence":"additional","affiliation":[{"name":"Division of Reproductive Health National Center for Chronic Disease Prevention and Health Promotion Centers for Disease Control and Prevention  Atlanta GA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,2,14]]},"reference":[{"key":"e_1_2_8_2_1","first-page":"3","article-title":"Ebola virus disease and pregnancy","volume":"25","author":"Burton R","year":"2015","journal-title":"Obstet Gynecol"},{"issue":"1","key":"e_1_2_8_3_1","first-page":"22","article-title":"Ebola hemorrhagic fever and pregnancy","volume":"179","author":"Mupapa K","year":"1999","journal-title":"J Infect Dis"},{"key":"e_1_2_8_4_1","unstructured":"World Health Organization (WHO).Ebola haemorrhagic fever in Zaire 1976. 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