{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T21:33:01Z","timestamp":1761514381196},"reference-count":25,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2019,5,2]],"date-time":"2019-05-02T00:00:00Z","timestamp":1556755200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010270","name":"Capital Health Research and Development of Special","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010270","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2019,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To determine whether polycystic ovary syndrome (<jats:styled-content style=\"fixed-case\">PCOS<\/jats:styled-content>) prevalence is increased among metabolically healthy obese (<jats:styled-content style=\"fixed-case\">MHO<\/jats:styled-content>) women.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A national epidemiologic survey in 10 provinces and municipalities of China between October 2007 and September 2011. Women were stratified into four groups according to metabolic health (assessment by Adult Treatment Panel <jats:styled-content style=\"fixed-case\">III<\/jats:styled-content>) and obesity (body mass index [<jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content>] \u226528): metabolically healthy nonobese (<jats:styled-content style=\"fixed-case\">MHNO<\/jats:styled-content>), metabolically unhealthy nonobese (<jats:styled-content style=\"fixed-case\">MUNO<\/jats:styled-content>), <jats:styled-content style=\"fixed-case\">MHO<\/jats:styled-content>, and metabolically unhealthy obese (<jats:styled-content style=\"fixed-case\">MUO<\/jats:styled-content>). <jats:styled-content style=\"fixed-case\">PCOS<\/jats:styled-content> was diagnosed via Rotterdam Criteria. Participants completed a questionnaire and underwent physical and transvaginal ultrasound examination. <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content>, blood pressure, glucose, and lipid profile were measured.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The survey included 3551 women. The <jats:styled-content style=\"fixed-case\">MHO<\/jats:styled-content> group had a higher prevalence of <jats:styled-content style=\"fixed-case\">PCOS<\/jats:styled-content> and chronic anovulation versus nonobese groups (all <jats:italic>P<\/jats:italic>&lt;0.05). Obesity was a risk factor for <jats:styled-content style=\"fixed-case\">PCOS<\/jats:styled-content> (odds ratio [<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>], 2.30; 95% confidence interval [<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>], 1.68\u20133.14, <jats:italic>P<\/jats:italic>&lt;0.05). Being metabolically unhealthy was a risk factor for <jats:styled-content style=\"fixed-case\">PCOS<\/jats:styled-content> (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>, 1.32; 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>, 1.09\u20131.60; <jats:italic>P<\/jats:italic>&lt;0.05). The <jats:styled-content style=\"fixed-case\">MHO<\/jats:styled-content> group had an increased risk of <jats:styled-content style=\"fixed-case\">PCOS<\/jats:styled-content> relative to the <jats:styled-content style=\"fixed-case\">MHNO<\/jats:styled-content> group (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>, 2.39; 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>, 1.42\u20134.02; <jats:italic>P<\/jats:italic>&lt;0.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">MHO<\/jats:styled-content> women had an increased risk of <jats:styled-content style=\"fixed-case\">PCOS<\/jats:styled-content> and chronic anovulation. Obesity might be an independent risk factor for these two disorders.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ijgo.12824","type":"journal-article","created":{"date-parts":[[2019,4,19]],"date-time":"2019-04-19T14:58:47Z","timestamp":1555685927000},"page":"164-169","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Prevalence of polycystic ovary syndrome in a metabolically healthy obese population"],"prefix":"10.1002","volume":"146","author":[{"given":"Liangshan","family":"Mu","sequence":"first","affiliation":[{"name":"Center for Reproductive Medicine Department of Obstetrics and Gynecology Peking University Third Hospital  Beijing China"},{"name":"Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproductive Technology  Beijing China"},{"name":"Key Laboratory of Assisted Reproduction Ministry of Education  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yue","family":"Zhao","sequence":"additional","affiliation":[{"name":"Center for Reproductive Medicine Department of Obstetrics and Gynecology Peking University Third Hospital  Beijing China"},{"name":"Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproductive Technology  Beijing China"},{"name":"Key Laboratory of Assisted Reproduction Ministry of Education  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rong","family":"Li","sequence":"additional","affiliation":[{"name":"Center for Reproductive Medicine Department of Obstetrics and Gynecology Peking University Third Hospital  Beijing China"},{"name":"Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproductive Technology  Beijing China"},{"name":"Key Laboratory of Assisted Reproduction Ministry of Education  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuchen","family":"Lai","sequence":"additional","affiliation":[{"name":"Center for Reproductive Medicine Department of Obstetrics and Gynecology Peking University Third Hospital  Beijing China"},{"name":"Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproductive Technology  Beijing China"},{"name":"Key Laboratory of Assisted Reproduction Ministry of Education  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hsun\u2010Ming","family":"Chang","sequence":"additional","affiliation":[{"name":"Center for Reproductive Medicine Department of Obstetrics and Gynecology Peking University Third Hospital  Beijing China"},{"name":"Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproductive Technology  Beijing China"},{"name":"Key Laboratory of Assisted Reproduction Ministry of Education  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jie","family":"Qiao","sequence":"additional","affiliation":[{"name":"Center for Reproductive Medicine Department of Obstetrics and Gynecology Peking University Third Hospital  Beijing China"},{"name":"Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproductive Technology  Beijing China"},{"name":"Key Laboratory of Assisted Reproduction Ministry of Education  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,5,2]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(14)60460-8"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.289.1.76"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(08)61531-7"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.168.15.1617"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.2337\/diabetes.47.5.699"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2006-0594"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc10-0665"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-159-11-201312030-00008"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.109.887521"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2011.04.047"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmq001"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.166.19.2081"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2007-1834"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2016.12.029"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.1990.tb00857.x"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2008.09.003"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/det262"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/deh098"},{"key":"e_1_2_8_20_1","first-page":"1719","article-title":"Clinical assessment of body hair growth in Japanese women. The relationship between a grade of hirsutism and the menstrual status","volume":"40","author":"Ichikawa Y","year":"1988","journal-title":"Nihon Sanka Fujinka Gakkai zasshi"},{"key":"e_1_2_8_21_1","first-page":"83","article-title":"Predictive values of body mass index and waist circumference for risk factors of certain related diseases in Chinese adults\u2013study on optimal cut\u2010\u2014f points of body mass index and waist circumference in Chinese adults","volume":"15","author":"Zhou BF","year":"2002","journal-title":"Biomed Environ Sci"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.285.19.2486"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dms030"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2013-2832"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2014-3885"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.116.004199"}],"container-title":["International Journal of Gynecology &amp; Obstetrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijgo.12824","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ijgo.12824","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijgo.12824","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,10]],"date-time":"2023-09-10T03:37:12Z","timestamp":1694317032000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/ijgo.12824"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,5,2]]},"references-count":25,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2019,8]]}},"alternative-id":["10.1002\/ijgo.12824"],"URL":"https:\/\/doi.org\/10.1002\/ijgo.12824","archive":["Portico"],"relation":{},"ISSN":["0020-7292","1879-3479"],"issn-type":[{"value":"0020-7292","type":"print"},{"value":"1879-3479","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,5,2]]},"assertion":[{"value":"2018-06-29","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-04-15","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-05-02","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}