{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,6]],"date-time":"2025-12-06T05:00:21Z","timestamp":1764997221343},"reference-count":20,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2019,5,7]],"date-time":"2019-05-07T00:00:00Z","timestamp":1557187200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology & Obste"],"published-print":{"date-parts":[[2019,8]]},"abstract":"Abstract<\/jats:title>Objective<\/jats:title>To assess the correlation between fetal blood vessel Doppler measurements and fetal anemia among Rhesus isoimmunized pregnancies after two intrauterine transfusions as a potential guide to therapy.<\/jats:p><\/jats:sec>Methods<\/jats:title>A prospective observational study was conducted among 30 women who attended a single hospital in India between April 2, 2015 and October 30, 2016. The participants underwent a third intrauterine transfusion based on a middle cerebral artery (MCA<\/jats:styled-content>) peak systolic velocity (PSV<\/jats:styled-content>) of greater than 1.50 multiples of the median (MoM). Cordocentesis was performed before the third intrauterine transfusion and hematocrit values correlated with the blood vessel Doppler measurements.<\/jats:p><\/jats:sec>Results<\/jats:title>The MCA PSV<\/jats:styled-content> MoM and fetal hematocrit MoM had a correlation coefficient of \u22120.43 (95% confidence interval \u22120.68 to 0.08; P<\/jats:italic>=0.017). The sensitivity, specificity, positive predictive value, and negative predictive value were 68%, 57%, 83%, and 33%, respectively. The descending aorta PSV<\/jats:styled-content> \u03b4 and fetal hematocrit \u03b4 had a correlation coefficient of \u22120.54 (95% confidence interval \u22120.75 to \u22120.23; P<\/jats:italic>=0.001). An area under the curve of 0.80 (standard error 0.085; P<\/jats:italic>=0.017) had 87% sensitivity and 57% specificity for diagnosing fetal anemia.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>The descending aorta PSV<\/jats:styled-content> could offer a useful diagnostic adjunct to MCA PSV<\/jats:styled-content> after two intrauterine transfusions.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ijgo.12825","type":"journal-article","created":{"date-parts":[[2019,4,20]],"date-time":"2019-04-20T12:53:24Z","timestamp":1555764804000},"page":"218-222","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Correlation of fetal blood vessel Doppler measurements with fetal anemia among Rhesus isoimmunized pregnancies after two intrauterine transfusions"],"prefix":"10.1002","volume":"146","author":[{"given":"Sarita","family":"Kumari","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynaecology All India Institute 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