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Publications from two recent multidisciplinary consensus conferences, one on sepsis in the non\u2010pregnant adult and the other on sepsis in the pregnant woman, concluded that the criteria for diagnosing sepsis should be clinically\u2010based, applicable at the bedside, and should not be laboratory\u2010based. Informed by reviews of the evidence, in 2017 <jats:styled-content style=\"fixed-case\">WHO<\/jats:styled-content> published a new definition of maternal sepsis based on the presence of suspected or confirmed infection. It also announced a Global Maternal and Neonatal Sepsis Initiative to identify the diagnostic criteria for the early identification, epidemiology, and disease classification of maternal sepsis. Standardizing the criteria for maternal sepsis optimizes clinical audit and research. It may facilitate the evaluation of the role of different clinical parameters and biomarkers in the diagnosis, earlier recognition and management of maternal infection and sepsis. Further work is required to develop an international consensus on the criteria for diagnosing maternal sepsis and any associated organ dysfunction.<\/jats:p>","DOI":"10.1002\/ijgo.12833","type":"journal-article","created":{"date-parts":[[2019,5,1]],"date-time":"2019-05-01T01:55:02Z","timestamp":1556675702000},"page":"39-42","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Maternal sepsis is an evolving challenge"],"prefix":"10.1002","volume":"146","author":[{"given":"Michael J.","family":"Turner","sequence":"first","affiliation":[{"name":"UCD Centre for Human Reproduction Coombe Women and Infants University Hospital  Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,5,17]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-017-4683-6"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2016.0290"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.CCM.0000050454.01978.3B"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2016.0287"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpobgyn.2013.04.003"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000000219"},{"issue":"1","key":"e_1_2_7_8_1","first-page":"1","article-title":"Saving Mothers\u2019 Lives: Reviewing maternal deaths to make motherhood safer: 2006\u20102008. 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