{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,18]],"date-time":"2026-04-18T11:15:51Z","timestamp":1776510951383,"version":"3.51.2"},"reference-count":19,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2019,6,10]],"date-time":"2019-06-10T00:00:00Z","timestamp":1560124800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology & Obste"],"published-print":{"date-parts":[[2019,8]]},"abstract":"Abstract<\/jats:title>Objective<\/jats:title>To evaluate group B streptococcus (GBS<\/jats:styled-content>) colonization prevalence and feasibility of intrapartum GBS<\/jats:styled-content> screening\/antibiotic prophylaxis (IAP<\/jats:styled-content>) in Cameroon, Africa.<\/jats:p><\/jats:sec>Methods<\/jats:title>Prospective cohort in the Cameroon Baptist Convention Health Services network. Maternity providers collected anogenital swabs from consenting term women in labor for testing by a rapid GBS<\/jats:styled-content>\u2010polymerase chain reaction (PCR<\/jats:styled-content>) system. Positive tests (GBS<\/jats:styled-content>+) resulted in initiation of intravenous ampicillin until delivery. Primary outcomes were GBS<\/jats:styled-content> prevalence and proportion of GBS<\/jats:styled-content>+ women receiving ampicillin before delivery and more than 4\u00a0hours before delivery.<\/jats:p><\/jats:sec>Results<\/jats:title>A total of 219 women were enrolled from January 10 to April 27, 2017. GBS<\/jats:styled-content> prevalence was 12.3% (95% confidence interval [CI<\/jats:styled-content>] 7.9\u201316.7) with GBS<\/jats:styled-content>+ women more likely to reside in urban areas (19.6% vs 9.7%, P<\/jats:italic>=0.004). Of 27 GBS<\/jats:styled-content>+ women, 19 (70.4%) received ampicillin before delivery and 14 (51.9%) 4\u00a0hours or longer before delivery. A median two doses of ampicillin (interquartile range [IQR<\/jats:styled-content>] 1\u20135) were given and started at a median of 105\u00a0minutes (IQR<\/jats:styled-content> 90\u2013155) after swab collection and 20\u00a0minutes (IQR<\/jats:styled-content> 10\u201345) after GBS<\/jats:styled-content> result. Of the 8 women who did not receive ampicillin, 7 (87.5%) delivered before test results.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>A GBS IAP<\/jats:styled-content> protocol is feasible in Cameroon and should be evaluated for widespread implementation in Cameroon and other low\u2010income countries to decrease GBS<\/jats:styled-content>\u2010related morbidity.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ijgo.12870","type":"journal-article","created":{"date-parts":[[2019,5,25]],"date-time":"2019-05-25T06:15:10Z","timestamp":1558764910000},"page":"238-243","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Prevalence of group B streptococcus anogenital colonization and feasibility of an intrapartum screening and antibiotic prophylaxis protocol in Cameroon, Africa"],"prefix":"10.1002","volume":"146","author":[{"given":"Akila","family":"Subramaniam","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology and Center for Women's Reproductive Health University of Alabama at Birmingham Birmingham AL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christina T.","family":"Blanchard","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology and Center for Women's Reproductive Health University of Alabama at Birmingham Birmingham AL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ekongefeyin S.N.","family":"Ngek","sequence":"additional","affiliation":[{"name":"University of Buea Buea Cameroon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rahel","family":"Mbah","sequence":"additional","affiliation":[{"name":"Cameroon Baptist Convention Health Services Bamenda Cameroon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edith","family":"Welty","sequence":"additional","affiliation":[{"name":"Cameroon Baptist Convention Health Services Bamenda Cameroon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Welty","sequence":"additional","affiliation":[{"name":"Cameroon Baptist Convention Health Services Bamenda Cameroon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jodie","family":"Dionne\u2010Odom","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases University of Alabama at Birmingham Birmingham AL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melissa","family":"Sander","sequence":"additional","affiliation":[{"name":"Bamenda Center for Health Promotion and Research Bamenda Cameroon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gregory","family":"Halle\u2010Ekane","sequence":"additional","affiliation":[{"name":"University of Buea Buea Cameroon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alan T.N.","family":"Tita","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology and Center for Women's Reproductive Health University of Alabama at Birmingham Birmingham AL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"the Cameroon Health Initiative","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,6,10]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(73)80604-3"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(73)80603-1"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(16)32429-2"},{"key":"e_1_2_8_5_1","first-page":"604","article-title":"The epidemiology of group B streptococcal colonization in pregnancy. 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