{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T03:13:33Z","timestamp":1773285213553,"version":"3.50.1"},"reference-count":16,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2019,6,19]],"date-time":"2019-06-19T00:00:00Z","timestamp":1560902400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100004423","name":"World Health Organization","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004423","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2019,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To assess the severity of complications following misoprostol used to induce abortion compared with other methods among women admitted for postabortion complications.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A cross\u2010sectional study of women who presented with complications of induced abortion at nine secondary and tertiary hospitals in South West Nigeria between April 1, 2013 and May 31, 2014. Face\u2010to\u2010face interviews were conducted and information on the current admission was extracted from patient records. Associations between abortion method used and severity of abortion complications were evaluated using \u03c7<jats:sup>2<\/jats:sup> and Fisher exact tests.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 522 women included in the study, 177 reported an induced abortion: 41 women (23.2%) had used misoprostol at the first attempt to induce abortion, whereas 79 (44.6%) women had undergone surgical abortion. Occurrence of fever (<jats:italic>P<\/jats:italic>=0.06), bleeding (<jats:italic>P<\/jats:italic>=0.3), and lower abdominal pain (<jats:italic>P<\/jats:italic>=0.32) was not significantly different between the misoprostol and surgical abortion\/other methods groups. Severe complications were rare with misoprostol, but more common among women in the surgical abortion\/other methods group. Maternal mortality occurred only among women in the surgical abortion\/other methods group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Use of misoprostol for induced abortion was associated with fewer complications and no maternal mortality compared with surgical abortion\/other methods.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ijgo.12877","type":"journal-article","created":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T14:09:28Z","timestamp":1559398168000},"page":"302-307","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["A prospective study of severity of complications associated with use of misoprostol and other abortion methods in South West Nigeria"],"prefix":"10.1002","volume":"146","author":[{"given":"Theresa A.","family":"Irinyenikan","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology State Specialist Hospital  Akure Nigeria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olabisi M.","family":"Loto","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Obafemi Awolowo University Teaching Hospital Complex  Ilesha Nigeria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Babawale","family":"Oluborode","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Obafemi Awolowo University  Ile\u2010Ife Nigeria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ibraheem","family":"Awowole","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Obafemi Awolowo University  Ile\u2010Ife Nigeria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Folasade A.","family":"Bello","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology College of Medicine University of Ibadan  Ibadan Nigeria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adetokunbo O.","family":"Fabamwo","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Lagos State University College of Medicine  Ikeja, Lagos Nigeria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philip","family":"Guest","sequence":"additional","affiliation":[{"name":"Institute for Population and Social Research  Salaya, Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bela","family":"Ganatra","sequence":"additional","affiliation":[{"name":"UNDP\u2010UNFPA\u2010UNICEF\u2010WHO\u2010World Bank Special Programme of Research Development and Research Training in Human Reproduction (HRP) WHO  Geneva Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bukola","family":"Fawole","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology College of Medicine University of Ibadan  Ibadan Nigeria"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,6,19]]},"reference":[{"key":"e_1_2_8_2_1","volume-title":"Unsafe Abortion: Global and Regional Estimates of the Incidence of Unsafe Abortion and Associated Mortality in 2000","author":"World Health Organization","year":"2004"},{"key":"e_1_2_8_3_1","unstructured":"SinghS.Adding it up: The Costs and benefits of investing in family planning and newborn health.https\u200b:\/\/www.guttm\u200bacher.org\/repor\u200bt\/adding-it-costs-and-benef\u200bits-inves\u200bting-family-plann\u200bing-and-mater\u200bnal-and-newbo\u200brn-health. 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