{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T12:48:20Z","timestamp":1777898900543,"version":"3.51.4"},"reference-count":13,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2019,7,9]],"date-time":"2019-07-09T00:00:00Z","timestamp":1562630400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology & Obste"],"published-print":{"date-parts":[[2019,9]]},"abstract":"Abstract<\/jats:title>Objective<\/jats:title>To compare the diagnostic accuracy of International Ovarian Tumor Analysis (IOTA<\/jats:styled-content>) simple rules and risk of malignancy index (RMI<\/jats:styled-content>\u00a01\/RMI<\/jats:styled-content>\u00a02) scoring to discriminate between benign and malignant adnexal masses.<\/jats:p><\/jats:sec>Methods<\/jats:title>Secondary analysis of a cohort of patients scheduled for surgery for adnexal masses in a tertiary center between April 2010 and March 2018. Ultrasound examinations were performed by general gynecologists within 24\u00a0hours prior to surgery to evaluate sonographic features. Demographic data and preoperative CA<\/jats:styled-content>\u00a0125 levels were recorded. IOTA<\/jats:styled-content> rules and RMI<\/jats:styled-content> scoring were applied to predict malignancy and prospectively recorded. Final diagnosis was based on pathological or intraoperative diagnosis.<\/jats:p><\/jats:sec>Results<\/jats:title>A total of 479 masses met the inclusion criteria and were retrieved from the database: 334 (69.7%) benign and 145 (30.3%) malignant. IOTA<\/jats:styled-content> rules could be applied to 392 (81.8%) masses and were inconclusive in 87 (18.2%). Sensitivity and specificity of IOTA<\/jats:styled-content> rules (83.8% and 92.0%, respectively) were significantly higher than RMI<\/jats:styled-content>\u00a01 (77.2% and 86.8%, respectively) and RMI<\/jats:styled-content>\u00a02 (82.1% and 82.6%, respectively).<\/jats:p><\/jats:sec>Conclusion<\/jats:title>IOTA<\/jats:styled-content> simple rules had higher diagnostic accuracy compared with RMI<\/jats:styled-content> to discriminate between benign and malignant adnexal masses; however, nearly 20% of IOTA<\/jats:styled-content> results were inconclusive and needed expert consultation.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ijgo.12891","type":"journal-article","created":{"date-parts":[[2019,6,17]],"date-time":"2019-06-17T18:45:57Z","timestamp":1560797157000},"page":"364-369","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":29,"title":["Comparison of the diagnostic accuracy of International Ovarian Tumor Analysis simple rules and the risk of malignancy index to discriminate between benign and malignant adnexal masses"],"prefix":"10.1002","volume":"146","author":[{"given":"Rapeepat","family":"Auekitrungrueng","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Chiang Mai University Chiang Mai Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dangcheewan","family":"Tinnangwattana","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Chiang Mai University Chiang Mai Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charuwan","family":"Tantipalakorn","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Chiang Mai University Chiang Mai Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cholaros","family":"Charoenratana","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Chiang Mai University Chiang Mai 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