{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T06:14:52Z","timestamp":1790403292674,"version":"4.1.0"},"reference-count":25,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2019,10,9]],"date-time":"2019-10-09T00:00:00Z","timestamp":1570579200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004861","name":"Mackay Memorial Hospital","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004861","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2019,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate risk factors associated with neonatal morbidity and mortality in pregnant women with preterm prelabor rupture of membranes (<jats:styled-content style=\"fixed-case\">PPROM<\/jats:styled-content>) after cervical cerclage.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective cohort study of singleton pregnancies with cervical insufficiency was conducted at a tertiary referral center in Taiwan from May 1, 2000 to July 31, 2017. Patients with <jats:styled-content style=\"fixed-case\">PPROM<\/jats:styled-content> after cerclage and delivered between 20 0\/7\u00a0days and 36 6\/7\u00a0days were recruited. Logistic and linear regression analyses were performed to evaluate various risk factors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Overall, 109 women were included. Mothers with a higher white blood cell count, a higher C\u2010reactive protein (<jats:styled-content style=\"fixed-case\">CRP<\/jats:styled-content>) level, a lower amniotic fluid index, and chorioamnionitis were significantly associated with neonatal morbidity. Neonatal mortality was related to oligohydramnios (adjusted odds ratio [<jats:styled-content style=\"fixed-case\">aOR<\/jats:styled-content>] 2.98, 95% confidence interval [<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>] 1.11\u20138.01) and chorioamnionitis (<jats:styled-content style=\"fixed-case\">aOR<\/jats:styled-content> 3.17, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 1.03\u20139.69). An elevated <jats:styled-content style=\"fixed-case\">CRP<\/jats:styled-content> level was associated with a shorter <jats:styled-content style=\"fixed-case\">PPROM<\/jats:styled-content> to delivery latency (adjusted B \u221216.64, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> \u221229.88 to \u22123.41), but cerclage retention more than 12\u00a0hours after <jats:styled-content style=\"fixed-case\">PPROM<\/jats:styled-content> was associated with a prolonged latency (adjusted B 17.21, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 3.25\u201331.18).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Oligohydramnios and chorioamnionitis are associated with neonatal mortality.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ijgo.12974","type":"journal-article","created":{"date-parts":[[2019,9,17]],"date-time":"2019-09-17T07:25:15Z","timestamp":1568705115000},"page":"382-388","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Factors associated with neonatal outcomes in preterm prelabor rupture of membranes after cervical cerclage"],"prefix":"10.1002","volume":"147","author":[{"given":"Ying\u2010Yu","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Mackay Memorial Hospital  Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chie\u2010Pein","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Mackay Memorial Hospital  Taipei 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