{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T07:02:28Z","timestamp":1791874948885,"version":"4.3.4"},"reference-count":19,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,5,15]],"date-time":"2020-05-15T00:00:00Z","timestamp":1589500800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2020,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To compare cervical pessaries plus vaginal progesterone versus long\u2010term tocolysis for preventing preterm birth for women with a short cervix.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Retrospective evaluation of women with singleton pregnancy who received cervical pessaries plus vaginal progesterone (combined group) or ritodrine hydrochloride (tocolysis group) for short cervix (\u226425\u00a0mm at 20\u201324\u00a0weeks, or \u226420\u00a0mm at 25\u201334\u00a0weeks) at a general hospital in Kagoshima, Japan, 2015\u20132019. The primary outcome was rate of preterm birth (&lt;36\u00a0weeks); secondary outcomes were maternal hospital admittance and treatment complications.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Data were evaluated from 95 women (combined group, n=43; tocolysis group, n=52). There was no significant difference in cervical length or gestational age at intervention between the groups. Overall, 3\/43 (7.0%) women delivered before 36 weeks in the combined group versus 16\/52 (30.8%) in the tocolysis group (relative risk, 0.56; 95% confidence interval, 0.41\u20130.76; <jats:italic>P<\/jats:italic>=0.004). Median maternal admittance was shorter in the combined group (6.6 vs 41.0\u00a0days, <jats:italic>P<\/jats:italic>&lt;0.001). Although 36\/43 (83.7%) women in the combined group reported increased vaginal discharge, no major complications occurred.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>A combination of pessaries and vaginal progesterone reduced the rate of preterm birth (&lt;36\u00a0weeks) for women with short cervix as compared with long\u2010term tocolysis.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ijgo.13164","type":"journal-article","created":{"date-parts":[[2020,4,13]],"date-time":"2020-04-13T19:34:27Z","timestamp":1586806467000},"page":"206-212","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Cervical pessary plus vaginal progesterone versus long\u2010term tocolysis for the prevention of preterm birth: An observational retrospective study"],"prefix":"10.1002","volume":"150","author":[{"given":"Masaki","family":"Tajima","sequence":"first","affiliation":[{"name":"Department of Obstetrics &amp; Gynecology Faculty of Medicine Kagoshima University  Kagoshima Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shintaro","family":"Yanazume","sequence":"additional","affiliation":[{"name":"Department of Obstetrics &amp; 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