{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T23:26:00Z","timestamp":1781220360882,"version":"3.54.1"},"reference-count":17,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,6,25]],"date-time":"2020-06-25T00:00:00Z","timestamp":1593043200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate maternal and perinatal outcomes in cases of third\u2010trimester malaria (TTM).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A parity\u2010matched comparative cohort study was carried out between December 1, 2018, and April 30, 2019, in three university teaching hospitals in Yaound\u00e9 (Cameroon). Women with and without TTM were followed up till delivery. The variables analyzed included maternal and gestational ages at delivery, the regimen of intermittent preventive treatment, usage of insecticide\u2010treated net, history of malaria recorded during pregnancy, birth and placenta weights, Apgar score, and early neonatal outcomes. Fisher exact test, t\u2010test, and logistic regression were used for comparison. <jats:italic>P<\/jats:italic>&lt;0.05 was considered statistically significant.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 3063 pregnant women, 130 (4.2%) had TTM. Adverse outcomes associated with TTM were maternal anemia (relative risk [RR] 10, 95% confidence interval [CI] 4.91\u201320.34), intrauterine fetal demise (RR 7.50, 95% CI 1.47\u201338.06), preterm delivery (RR 4.50, 95% CI 2.37\u20138.51), low birth weight (adjusted RR 2.88, 95% CI 1.34\u20136.19), neonatal asphyxia especially if delivery occurred during parenteral treatment (RR 5.18, 95% CI 2.56\u201310.48), transfer of the newborn to the neonatal intensive care unit (RR 4.38, 95% CI 2.59\u20137.42), and intrapartum or early neonatal death (RR 4.18, 95% CI 1.48\u201311.74).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>TTM was associated with adverse perinatal outcome especially if labor started during parenteral treatment.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ijgo.13261","type":"journal-article","created":{"date-parts":[[2020,6,8]],"date-time":"2020-06-08T12:30:57Z","timestamp":1591619457000},"page":"103-108","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Malaria in the third trimester and maternal\u2010perinatal outcome"],"prefix":"10.1002","volume":"151","author":[{"given":"Elie","family":"Nkwabong","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Faculty of Medicine and Biomedical Sciences &amp; University Teaching Hospital Yaound\u00e9 Cameroon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diane N.","family":"Mayane","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Faculty of Medicine and Biomedical Sciences Yaound\u00e9 Cameroon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esther","family":"Meka","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Faculty of Medicine and Biomedical Sciences &amp; Gynaeco\u2010Obstetric and Pediatric Hospital Yaound\u00e9 Yaound\u00e9 Cameroon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felix","family":"Essiben","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Faculty of Medicine and Biomedical Sciences &amp; Gynaeco\u2010Obstetric and Pediatric Hospital Yaound\u00e9 Yaound\u00e9 Cameroon"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,6,25]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(07)70021-X"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2003.69.574"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0199415"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/8396091"},{"key":"e_1_2_8_6_1","first-page":"316","article-title":"Accuracy of the rapid diagnostic test for malaria among pregnant women in the Kitutu Health Zone in eastern RD Congo","volume":"28","author":"Mulongo Mbarambara P","year":"2018","journal-title":"Med Sante Trop"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.semperi.2019.03.018"},{"key":"e_1_2_8_8_1","first-page":"328","article-title":"Management of malaria in pregnancy","volume":"146","author":"Rogerson SJ","year":"2017","journal-title":"Indian J Med Res"},{"key":"e_1_2_8_9_1","first-page":"D3321","article-title":"The treatment of malaria","volume":"163","author":"Visser BJ","year":"2019","journal-title":"Ned Tijdschr Geneeskd"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a025551"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12936-019-2779-x"},{"key":"e_1_2_8_12_1","first-page":"1","article-title":"Variations in the leukocyte and cytokine profiles between placental and maternal circulation in pregnancy\u2010associated malaria","volume":"9","author":"Okamgba OC","year":"2018","journal-title":"Res Rep Trop Med"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0258(20000415)19:7<901::AID-SIM405>3.0.CO;2-L"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1080\/147670500231989"},{"key":"e_1_2_8_15_1","first-page":"577","article-title":"Sickle cell disease and pregnancy: Obstetrical prognosis from 21 observations in a reference maternity in Niger","volume":"5411","author":"Nayama M","year":"2007","journal-title":"Med Afr Noire"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/6712685"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.4103\/0300-1652.188327"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciy1073"}],"container-title":["International Journal of Gynecology &amp; Obstetrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fijgo.13261","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijgo.13261","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ijgo.13261","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijgo.13261","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,5]],"date-time":"2023-09-05T02:34:25Z","timestamp":1693881265000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/ijgo.13261"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6,25]]},"references-count":17,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,10]]}},"alternative-id":["10.1002\/ijgo.13261"],"URL":"https:\/\/doi.org\/10.1002\/ijgo.13261","archive":["Portico"],"relation":{},"ISSN":["0020-7292","1879-3479"],"issn-type":[{"value":"0020-7292","type":"print"},{"value":"1879-3479","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,6,25]]},"assertion":[{"value":"2019-09-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-06-03","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-06-25","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}