{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T20:21:36Z","timestamp":1780690896452,"version":"3.54.1"},"reference-count":22,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,8,18]],"date-time":"2020-08-18T00:00:00Z","timestamp":1597708800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2020,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To assess the baseline types of HPV infection among HIV\u2010positive and HIV\u2010negative women in western Kenya undergoing cryotherapy or loop electrosurgical excision procedure (LEEP) for cervical intraepithelial neoplasia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A prospective observational study was conducted of baseline HPV characteristics of women undergoing visual inspection with acetic acid (VIA) and cryotherapy or LEEP. After a positive VIA in HIV\u2010positive and HIV\u2010negative women, data on demographics, CD4 count, and use of antiretroviral therapy and a cervical swab were collected. HPV typing was performed using the Roche Linear Array.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 175 participants, 86 (49.1%) were HIV\u2010positive and had a higher prevalence of low\u2010risk HPV types (odds ratio [OR] 5.28, <jats:italic>P<\/jats:italic>=0.005) compared with HIV\u2010negative women. The most common high\u2010risk (HR)\u2010HPV types in HIV\u2010positive women were HPV 16 (13.9%) and HPV 18 (11.1%). HIV\u2010positive women requiring LEEP were more likely to have HR\u2010HPV types (OR 6.67, <jats:italic>P<\/jats:italic>=0.012) and to be infected with multiple HR\u2010HPV types (OR 7.79, <jats:italic>P<\/jats:italic>=0.024) compared to those undergoing cryotherapy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>HIV\u2010positive women requiring LEEP versus cryotherapy had a higher prevalence of any HR\u2010HPV type and multiple HR\u2010HPV types. There were no such differences in HPV types identified among HIV\u2010negative women.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ijgo.13330","type":"journal-article","created":{"date-parts":[[2020,7,27]],"date-time":"2020-07-27T05:21:39Z","timestamp":1595827299000},"page":"279-286","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Detection of types of HPV among HIV\u2010infected and HIV\u2010uninfected Kenyan women undergoing cryotherapy or loop electrosurgical excision procedure"],"prefix":"10.1002","volume":"151","author":[{"given":"Elkanah O.","family":"Orang\u2019o","sequence":"first","affiliation":[{"name":"Moi University Eldoret Kenya"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jordan P.","family":"Emont","sequence":"additional","affiliation":[{"name":"Brown University Providence RI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aaron 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