{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T11:37:53Z","timestamp":1775734673522,"version":"3.50.1"},"reference-count":23,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,9,30]],"date-time":"2020-09-30T00:00:00Z","timestamp":1601424000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To compare uterine artery pulsatility index (UTPI) at 6\u00a0weeks of pregnancy following in vitro fertilization (IVF) and embryo transfer (ET) between clinical pregnancies that resulted in a miscarriage and those that were ongoing beyond 12\u00a0weeks.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A prospective observational study was conducted in an IVF unit at Prince of Wales Hospital, Hong Kong, between December 1, 2017 and December 31, 2019. UTPI was measured at 6\u00a0weeks of pregnancy among women who conceived following IVF\/ET.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among 153 participants, 22 (14.4%) had a miscarriage whereas 131 (85.6%) had an ongoing pregnancy beyond 12\u00a0weeks. Median UTPI in pregnancies that ended in a miscarriage was significantly lower than those that progressed beyond 12\u00a0weeks (2.1, IQR 1.9\u20132.4 vs 2.50, IQR 2.2\u20132.9, respectively; <jats:italic>P<\/jats:italic>&lt;0.001). The likelihood of the pregnancy ending in a miscarriage when the UTPI was above the 75th percentile (&gt;2.9), between the 25th\u201375th percentiles (2.2\u20132.9), and below the 25th percentile (&lt;2.2) was 0%, 13.2%, and 27.7%, respectively (<jats:italic>P<\/jats:italic>=0.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>IVF pregnancies that resulted in a miscarriage were associated with reduced resistance to uterine artery blood flow at 6\u00a0weeks of pregnancy.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ijgo.13371","type":"journal-article","created":{"date-parts":[[2020,9,27]],"date-time":"2020-09-27T10:38:09Z","timestamp":1601203089000},"page":"249-255","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Comparison of uterine artery Doppler measurements at 6\u00a0weeks of pregnancy after IVF between pregnancies that resulted in miscarriage and ongoing pregnancies"],"prefix":"10.1002","volume":"152","author":[{"given":"Jun","family":"Guo","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Assisted Reproductive Technology Unit Prince of Wales Hospital The Chinese University of Hong Kong Shatin, Hong Kong SAR China"},{"name":"Department of Obstetrics and Gynecology Maternal Fetal Medicine Unit Prince of Wales Hospital The Chinese University of Hong Kong Shatin, Hong Kong SAR China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Piya","family":"Chaemsaithong","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Maternal Fetal Medicine Unit Prince of Wales Hospital The Chinese University of Hong Kong Shatin, Hong Kong SAR China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Assisted Reproductive Technology Unit Prince of Wales Hospital The Chinese University of Hong Kong Shatin, Hong Kong SAR China"},{"name":"Department of Gynecology The First Affiliated Hospital of Chongqing Chongqing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacqueline P.W.","family":"Chung","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Assisted Reproductive Technology Unit Prince of Wales Hospital The Chinese University of Hong Kong Shatin, Hong Kong SAR China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junhong","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Ultrasound Hubei Women and Children\u2019s Hospital Wuhan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liona C.Y.","family":"Poon","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Maternal Fetal Medicine Unit Prince of Wales Hospital The Chinese University of Hong Kong Shatin, Hong Kong SAR China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tin Chiu","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Assisted Reproductive Technology Unit Prince of Wales Hospital The Chinese University of Hong Kong Shatin, Hong Kong SAR 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