{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T05:54:07Z","timestamp":1768888447901,"version":"3.49.0"},"reference-count":23,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2020,12,31]],"date-time":"2020-12-31T00:00:00Z","timestamp":1609372800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To analyze the clinical profile and prognosis of primary Fallopian tube cancer (PFTC) in order to improve earlier diagnosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In this retrospective study, 57 women with PFTC were assessed from 2006 to 2016. Pathology, clinical index, recurrence, and survival were analyzed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Mean age was 57.35\u00a0\u00b1\u00a09.01\u00a0years, and 73% (19\/26) of the patients with early\u2010stage PFTC (I\/II) were aged less than 60\u00a0years. Of patients who presented with abnormal vaginal bleeding, 75% (9\/12) were at an early stage and their condition was often misdiagnosed as endometrial carcinoma preoperatively. In patients with Stages I\/II and Stages III\/IV PFTC, 59.09% (13\/22) and 96.43% (27\/28), respectively, had adnexal masses on color Doppler ultrasonography. The 5\u2010year overall survival (OS) and disease\u2010free survival rates were 69.23% and 44.23%, respectively, and univariate analysis showed that tumor stage and residual tumor size significantly affected the two survival rates.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Primary Fallopian tube cancer is more likely to be misdiagnosed in patients aged less than 60\u00a0years or those presenting with vaginal bleeding at the premenopausal stage. Magnetic resonance imaging, cervical smear, and endometrial brush may be helpful for early PFTC diagnosis. Satisfactory cytoreductive surgery is critical because tumor stage and residual tumor size are significantly associated with the OS rate.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ijgo.13497","type":"journal-article","created":{"date-parts":[[2020,11,24]],"date-time":"2020-11-24T08:55:17Z","timestamp":1606208117000},"page":"405-411","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Clinical characteristics of primary Fallopian tube carcinoma: A single\u2010institution retrospective study of 57 cases"],"prefix":"10.1002","volume":"153","author":[{"given":"Zhihua","family":"Ma","sequence":"first","affiliation":[{"name":"Department of Gynecology &amp; Obstetrics The First Affiliated Hospital of Xi\u2019an Jiaotong University Xi\u2019an, Shaanxi China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li","family":"Gao","sequence":"additional","affiliation":[{"name":"Department of Gynecology &amp; Obstetrics The First Affiliated Hospital of Xi\u2019an Jiaotong University Xi\u2019an, Shaanxi China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Han","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Gynecology &amp; Obstetrics The First Affiliated Hospital of Xi\u2019an Jiaotong University Xi\u2019an, Shaanxi China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jie","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Pathology The First Affiliated Hospital of Xi\u2019an Jiaotong University Xi\u2019an, Shaanxi China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guanjun","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Pathology The First Affiliated Hospital of Xi\u2019an Jiaotong University Xi\u2019an, Shaanxi China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan","family":"Xue","sequence":"additional","affiliation":[{"name":"Department of Gynecology &amp; Obstetrics The First Affiliated Hospital of Xi\u2019an Jiaotong University Xi\u2019an, Shaanxi China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,12,31]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tjog.2019.07.008"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2018.01.030"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djx263"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tjog.2014.07.003"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/IGC.0000000000000648"},{"issue":"2","key":"e_1_2_9_7_1","first-page":"99","article-title":"Prognostic factors of primary fallopian tube carcinoma","volume":"22","author":"Akkaya E","year":"2018","journal-title":"Contemp Oncol (Pozn)"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anndiagpath.2012.10.001"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1200\/JOP.18.00662"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/IGC.0000000000000316"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-016-4035-8"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0142(19980301)82:5<893::AID-CNCR14>3.0.CO;2-W"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1359-6349(09)70018-7"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/sim.4780050306"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/6930986"},{"issue":"3","key":"e_1_2_9_16_1","first-page":"363","article-title":"Fallopian tube carcinoma in\u2010situ in endometrial curettage","volume":"13","author":"Nishith N","year":"2018","journal-title":"Iran J Pathol"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.30537"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/IGC.0000000000001321"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/PGP.0000000000000109"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pathol.2019.10.007"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.5144\/0256-4947.2014.444"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.2013.402"},{"issue":"6","key":"e_1_2_9_23_1","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/j.jogoh.2019.03.017","article-title":"Management of epithelial cancer of the ovary, fallopian tube, and primary peritoneum. Long text of the Joint French Clinical Practice Guidelines issued by FRANCOGYN, CNGOF, SFOG, and GINECO\u2010ARCAGY, and endorsed by INCa. 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