{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T17:09:20Z","timestamp":1785863360550,"version":"3.56.0"},"reference-count":25,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2020,12,29]],"date-time":"2020-12-29T00:00:00Z","timestamp":1609200000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>OBJECTIVE<\/jats:title><jats:p>To ascertain the threshold value for anti\u2010M\u00fcllerian hormone (AMH) in the diagnosis of polycystic ovarian syndrome (PCOS) in an Indian population.<\/jats:p><\/jats:sec><jats:sec><jats:title>METHODS<\/jats:title><jats:p>A retrospective observational study was carried out on infertile women at the Department of Reproductive Medicine and Surgery at a tertiary hospital from January 2017 to November 2019. Serum AMH was analyzed with Access AMH chemiluminescent immunoassay. Receiver operating characteristic curves were used to calculate the diagnostic threshold value of serum AMH in two age groups: 20\u201329 and 30\u201339\u00a0years.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>Of 688 women, 200 (29.1%) were diagnosed with PCOS by the Rotterdam criteria: 98\/282 (34.8%) aged 20\u201329\u00a0years and 102\/406 (25.4%) aged 30\u201339\u00a0years. Mean serum AMH was 5.07\u00a0\u00b1\u00a03.97 and 4.330\u00a0\u00b1\u00a07.15\u00a0ng\/ml in women aged 20\u201329 and 30\u201339\u00a0years, respectively. A threshold value of serum AMH above 3.75\u00a0ng\/ml was predictive of PCOS by Youden's <jats:italic>J<\/jats:italic> statistics in the entire cohort, whereas it was 5.46 and 3.46\u00a0ng\/ml in women aged 20\u201329 and 30\u201339\u00a0years, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSION<\/jats:title><jats:p>Serum AMH of 5.46 and 3.46\u00a0ng\/ml in women aged 20\u201329 and 30\u201339\u00a0years, respectively, can be used to diagnose PCOS when there is a diagnostic dilemma in the Rotterdam criteria.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ijgo.13515","type":"journal-article","created":{"date-parts":[[2020,12,4]],"date-time":"2020-12-04T19:57:58Z","timestamp":1607111878000},"page":"443-448","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Age\u2010related diagnostic threshold of anti\u2010M\u00fcllerian hormone for polycystic ovarian syndrome"],"prefix":"10.1002","volume":"153","author":[{"given":"Vivek","family":"Kakkad","sequence":"first","affiliation":[{"name":"Department of Reproductive Medicine and Surgery Sri Ramachandra Medical Centre and Research Institute Chennai Tamil Nadu India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nellepalli Sanjeeva","family":"Reddy","sequence":"additional","affiliation":[{"name":"Department of Reproductive Medicine and Surgery Sri Ramachandra Medical Centre and Research Institute Chennai Tamil Nadu India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2601-7594","authenticated-orcid":false,"given":"Harsh","family":"Nihlani","sequence":"additional","affiliation":[{"name":"Department of Reproductive Medicine and Surgery Sri Ramachandra Medical Centre and Research Institute Chennai Tamil Nadu India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tejas","family":"Gundewar","sequence":"additional","affiliation":[{"name":"Department of Reproductive Medicine and Surgery Sri Ramachandra Medical Centre and Research Institute Chennai Tamil Nadu India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,12,29]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(07)61345-2"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2006-0178"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/dew218"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/dep399"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/dey256"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2006-1054"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.90684.2008"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2003-030727"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2007.06.023"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2006-1582"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(16)48552-3"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwj063"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mefs.2010.08.005"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/aogs.12247"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1507\/endocrj.EJ12-0055"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/det015"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2015.12.023"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/der297"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/des213"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13224-017-1066-4"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/dex226"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0203129"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.4103\/jhrs.JHRS_149_18"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2019.07.1116"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics9040136"}],"container-title":["International Journal of Gynecology &amp; 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