{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T02:11:40Z","timestamp":1782439900330,"version":"3.54.5"},"reference-count":18,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2021,2,2]],"date-time":"2021-02-02T00:00:00Z","timestamp":1612224000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To investigate the relationship between the number of hyperintense foci of T2\u2010weighted imaging (T2WI) and the efficacy of high\u2010intensity focused ultrasound (HIFU) in the treatment of adenomyosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This prospective cohort study enrolled 102 patients with adenomyosis. Participants were classified into two groups: 50 patients in whom the number of hyperintense foci on magnetic resonance imaging (MRI) T2WI was more than five were placed in the &gt;5 group and 52 patients in whom the number of hyperintense foci on MRI T2WI was five or fewer were placed in the \u22645 group. Uterine fibroid symptoms (UFS) and visual analog scale (VAS) scores were recorded as indicators for the course of adenomyosis treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among the enrolled patients, 84 received HIFU treatment and were followed up. At 6, 12, 24, and 36\u00a0months after HIFU treatment, the UFS score of women in the &gt;5 group was higher than that of the patients in the \u22645 group (<jats:italic>P\u00a0<\/jats:italic>&lt;\u00a00.05). The ablation rate of MRI T2WI in the hyperintense foci \u22645 group was higher than the hyperintense foci &gt;5 group (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Number of MRI T2WI hyperintense foci is a factor affecting the ablation rate and the clinical efficacy of HIFU treatment in women with adenomyosis. It is likely to be a predictor of the efficacy of HIFU in adenomyosis treatment.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ijgo.13587","type":"journal-article","created":{"date-parts":[[2021,1,15]],"date-time":"2021-01-15T01:30:14Z","timestamp":1610674214000},"page":"241-247","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Magnetic resonance imaging T2WI hyperintense foci number and the prognosis of adenomyosis after high\u2010intensity focused ultrasound treatment"],"prefix":"10.1002","volume":"154","author":[{"given":"Cheng\u2010chao","family":"Du","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Affiliated Hospital of North Sichuan Medical College Nanchong China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu\u2010qi","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Affiliated Hospital of North Sichuan Medical College Nanchong China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Da\u2010cheng","family":"Qu","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Affiliated Hospital of North Sichuan Medical College Nanchong China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liu\u2010peng","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Affiliated Hospital of North Sichuan Medical College Nanchong China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Affiliated Hospital of North Sichuan Medical College Nanchong China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong\u2010gui","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Affiliated Hospital of North Sichuan Medical College Nanchong China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,2,2]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/aogs.13159"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0889-8545(21)00148-0"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2011.05.036"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ultsonch.2015.05.033"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2010.10.020"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000002443"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2017.02.001"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.3109\/02656736.2016.1149232"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpobgyn.2014.04.010"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/16.11.2427"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiographics.19.suppl_1.g99oc13s147"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1148\/rg.251045060"},{"key":"e_1_2_8_14_1","first-page":"1146","article-title":"Diagnostic findings in adenomyosis: a pictorial review on the major concerns","volume":"19","author":"Graziano A","year":"2015","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ultsonch.2016.11.022"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ultrasmedbio.2019.08.022"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ultsonch.2015.05.024"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2013.08.022"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1080\/02656736.2017.1326634"}],"container-title":["International Journal of Gynecology &amp; 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