{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T15:22:08Z","timestamp":1779290528402,"version":"3.51.4"},"reference-count":22,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,2,12]],"date-time":"2021-02-12T00:00:00Z","timestamp":1613088000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To evaluate the role of appendectomy in surgical excision of endometriosis and to assess complications associated with appendectomy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Retrospective study of women undergoing appendectomy for pelvic pain and\/or endometriosis during a primary gynecologic procedure.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Record review was performed for 609 women who underwent appendectomy between 2013 and 2019 for pelvic pain (6.9%, 42\/609), stage I\u2013II endometriosis (63.7%, 388\/609), or stage III\u2013IV endometriosis (29.4%, 179\/609). Appendiceal endometriosis (AppE) was present in 14.9% (91\/609); 2.4% without endometriosis (1\/42, reference group), 7.0% with stage I\u2013II endometriosis (27\/388, odds ratio [OR] 3.06, 95% confidence interval [CI] 0.41\u201323.11,\n                      <jats:italic>P\u00a0<\/jats:italic>\n                      =\u00a00.278), and 35.2% with stage III\u2013IV endometriosis (63\/179, OR 22.24, 95% CI 2.99\u2013165.40,\n                      <jats:italic>P\u00a0<\/jats:italic>\n                      =\u00a00.002). AppE was significantly associated with endometriosis present in other locations (OR 5.27, 95% CI 2.66\u201310.43,\n                      <jats:italic>P\u00a0<\/jats:italic>\n                      &lt;\u00a00.001). The predicted probability of identifying AppE ranged from 6% with 0 positive endometriosis sites to 56% when 4 or more sites were identified. There were no complications related to the performance of an appendectomy.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Women with chronic pelvic pain and\/or endometriosis have an increased risk of AppE. Modern appendectomy at the time of gynecologic surgery is safe, with no associated complications in this study. Our findings support the consideration of appendectomy as part of the comprehensive surgical management of endometriosis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ijgo.13614","type":"journal-article","created":{"date-parts":[[2021,1,23]],"date-time":"2021-01-23T04:32:18Z","timestamp":1611376338000},"page":"526-531","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Appendectomy in the surgical management of women with endometriosis and pelvic pain"],"prefix":"10.1002","volume":"154","author":[{"given":"Whitney Trotter","family":"Ross","sequence":"first","affiliation":[{"name":"Obstetrics and Gynecology Division of Minimally Invasive Gynecologic Surgery Washington University in St. Louis St. Louis MO USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amanda","family":"Chu","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology Division of Minimally Invasive Gynecologic Surgery Washington University in St. Louis St. Louis MO USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linda","family":"Li","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology Division of Minimally Invasive Gynecologic Surgery Penn State Health Hershey Medical Center Hershey PA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Allen R.","family":"Kunselman","sequence":"additional","affiliation":[{"name":"Public Health Sciences Penn State Hershey College of Medicine Hershey PA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerald J.","family":"Harkins","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology Division of Minimally Invasive Gynecologic Surgery Penn State Health Hershey Medical Center Hershey PA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Timothy A.","family":"Deimling","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology Division of Minimally Invasive Gynecologic Surgery Penn State Health Hershey Medical Center Hershey PA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea S.","family":"Benton","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology Division of Minimally Invasive Gynecologic Surgery Penn State Health Hershey Medical Center Hershey PA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,2,12]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000001422"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0889\u20108545(02)00050\u20105"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2005.12.076"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2005.03.003"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijgo.12286"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2013.04.017"},{"issue":"5","key":"e_1_2_8_8_1","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1097\/00006250-200511000-00060","article-title":"ACOG Committee Opinion #323: Elective coincidental appendectomy","volume":"106","author":"American Congress of Obstetricians and Gynecologists","year":"2005","journal-title":"Obstet Gynecol"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/GCO.0000000000000466"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2020.01.009"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e3181758ec6"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1074-3804(05)80007-6"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(03)00936-0"},{"issue":"4","key":"e_1_2_8_14_1","first-page":"307","article-title":"Routine appendectomy in extensive gynecologic operations","volume":"162","author":"Westermann C","year":"1986","journal-title":"Surg Gynecol Obstet"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1074-3804(05)60618-4"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2010.08.042"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0020-7292(97)00215-4"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000002469"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2010.02.044"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2014.04.002"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1479-828X.2007.00811.x"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1590\/1984\u20100462\/;2019;37;2;00012"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2015.06.089"}],"container-title":["International Journal of Gynecology &amp; 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