{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T14:22:15Z","timestamp":1781101335001,"version":"3.54.1"},"reference-count":25,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2021,3,24]],"date-time":"2021-03-24T00:00:00Z","timestamp":1616544000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2022,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To identify whether the time interval from insemination to ovulation (I\u2010O interval) affects outcome after intrauterine insemination with donor sperm (IUI\u2010D).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective study was conducted in a public assisted reproductive medicine center between January, 2014 and December, 2016 in Xi'an, China. The data were collected from the medical records and generalized estimating equations (GEEs) were used to evaluate the effects of various variables on IUI outcome.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 2091 IUI\u2010D cycles from 1165 couples were included in this study. Multiple predictors were identified for (live birth rate) LBR. The I\u2010O interval was the predictor for LBR. An I\u2010O interval \u226519\u00a0h significantly decreased CPR (odds ratio [OR], 95% confidence interval [CI]: 0.29, 0.17\u20130.48) and LBR (OR, 95% CI: 0.32, 0.19\u20130.55). The presence of at least two follicles \u226518\u00a0mm on ovulation day significantly increased the LBR (OR, 95%CI: 1.27, 1.01\u20131.60). Women aged 35\u00a0years and older had a significantly decreased LBR (OR, 95% CI: 0.61, 0.38\u20130.98).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The I\u2010O interval, a new prognostic factor, in combination with the woman's age and number of mature follicles, can predict the outcome after IUI\u2010D. IUI\u2010D is best performed within 19\u00a0h of I\u2010O interval for a higher probability of clinical pregnancy and live birth.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ijgo.13641","type":"journal-article","created":{"date-parts":[[2021,2,6]],"date-time":"2021-02-06T07:01:39Z","timestamp":1612594899000},"page":"341-348","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["The interval between insemination and ovulation predicts outcome after intrauterine insemination with donor sperm (IUI\u2010D)"],"prefix":"10.1002","volume":"156","author":[{"given":"Xin","family":"Mu","sequence":"first","affiliation":[{"name":"The Assisted Reproductive Medicine Center Northwest Women's and Children's Hospital  Xi'an People's Republic of China"},{"name":"Center for Translational Medicine The First Affiliated Hospital of Xi'an Jiaotong University  Xi'an People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Wang","sequence":"additional","affiliation":[{"name":"The Assisted Reproductive Medicine Center Northwest Women's and Children's Hospital  Xi'an People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pei\u2010Jun","family":"Liu","sequence":"additional","affiliation":[{"name":"Center for Translational Medicine The First Affiliated Hospital of Xi'an Jiaotong University  Xi'an People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan\u2010Zi","family":"Shi","sequence":"additional","affiliation":[{"name":"The Assisted Reproductive Medicine Center Northwest Women's and Children's Hospital  Xi'an People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,3,24]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/ppe.12538"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2018.09.012"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpobgyn.2018.08.003"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gyobfe.2012.07.007"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rbmo.2017.01.016"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jogoh.2019.05.006"},{"issue":"2","key":"e_1_2_9_8_1","first-page":"93","article-title":"Influence of BMI and smoking on IUI outcome with partner and donor sperm","volume":"9","author":"Huyghe S","year":"2017","journal-title":"Facts Views Vis Obgyn"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rbmo.2017.05.018"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2014.05.018"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/hropen\/hoy002"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rbmo.2017.05.005"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2003.09.081"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/jog.13625"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmx041"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/deu022"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwf215"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rbmo.2018.08.002"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-011-1950-6"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2013.07.022"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mefs.2013.10.002"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1701-2163(16)35110-6"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(16)44888-0"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2014.01.016"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10815-008-9247-9"},{"issue":"1","key":"e_1_2_9_26_1","first-page":"66","article-title":"Associated factors to pregnancy in intrauterine insemination","volume":"24","author":"Vargas\u2010Tominaga L","year":"2020","journal-title":"JBRA Assist Reprod"}],"container-title":["International Journal of Gynecology &amp; 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