{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,30]],"date-time":"2025-12-30T23:01:20Z","timestamp":1767135680383,"version":"build-2238731810"},"reference-count":30,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,3,24]],"date-time":"2021-03-24T00:00:00Z","timestamp":1616544000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To compare the effectiveness and safety of repeat misoprostol versus expectant management in women with first\u2010trimester incomplete miscarriage who have been initially treated with misoprostol.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The study was an open\u2010labeled randomized controlled trial including women with an incomplete first\u2010trimester miscarriage after administration of misoprostol. The participants were randomly assigned to vaginal misoprostol or expectant management using a computer\u2010generated table of random numbers. The primary outcome was the number of women with a complete miscarriage at 1\u00a0week.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Eighty\u2010eight women (44 women in each group) were analyzed. The rate of complete miscarriage at 1\u00a0week was significantly higher in the misoprostol group than the expectant management group\u201429 (69.0%) versus 7 (16.7%) (\n                      <jats:italic>P\u00a0<\/jats:italic>\n                      &lt;\u00a00.001), respectively. Women in the misoprostol group were more satisfied (7.00\u00a0\u00b1\u00a00.77 vs 4.57\u00a0\u00b1\u00a01.61,\n                      <jats:italic>P\u00a0<\/jats:italic>\n                      &lt;\u00a00.001) but reported more pain (7.95\u00a0\u00b1\u00a01.85 vs 5.26\u00a0\u00b1\u00a01.08,\n                      <jats:italic>P\u00a0<\/jats:italic>\n                      &lt;\u00a00.001) than women in the expectant group. The misoprostol group reported more adverse effects than the expectant management group (\n                      <jats:italic>P\u00a0<\/jats:italic>\n                      &lt;\u00a00.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In women with an incomplete first\u2010trimester miscarriage who were initially treated with misoprostol, repeat administration of misoprostol was more effective than expectant management for achieving complete miscarriage at 1\u00a0week. However, misoprostol was associated with more adverse effects.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Registration site and number<\/jats:title>\n                    <jats:p>Clinicaltrials.gov: NCT03148561.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ijgo.13652","type":"journal-article","created":{"date-parts":[[2021,2,22]],"date-time":"2021-02-22T03:15:02Z","timestamp":1613963702000},"page":"558-564","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Retracted: Misoprostol versus expectant management in women with incomplete first\u2010trimester miscarriage after failed primary misoprostol treatment: A randomized clinical trial"],"prefix":"10.1002","volume":"154","author":[{"given":"Mohammed K.","family":"Ali","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Faculty of Medicine Assiut University 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