{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T11:43:50Z","timestamp":1790077430196,"version":"4.0.1"},"reference-count":25,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,10,4]],"date-time":"2021-10-04T00:00:00Z","timestamp":1633305600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To compare, in terms of anatomical, functional, and sexual aspects, two types of treatment for women with vaginal agenesis: progressive dilation or surgical neovaginoplasty.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Women with vaginal agenesis underwent either dilation treatment using the Frank method or surgical treatment using the modified Abb\u00e9\u2010McIndoe technique with oxidized cellulose. Patients were evaluated 3\u20136\u00a0months after treatment for a follow\u2010up including medical history, physical examination, general satisfaction, clinical aspect of the vagina, Female Sexual Function Index, and three\u2010dimensional pelvic floor ultrasound.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In total, 20 women with vaginal agenesis were included in the present study; nine in the dilation group and 11 in the surgical group. A comparison between the groups (vaginal dilation and surgical neovaginoplasty) showed efficacy in neovagina formation after both treatments, with a statistically significant difference between the pre\u2010 and post\u2010treatment periods (\n                      <jats:italic>P<\/jats:italic>\n                      value pre\u2010\u00a0\u00d7\u00a0post\u2010dilation group &lt;0.0001 and\n                      <jats:italic>P<\/jats:italic>\n                      value pre\u2010\u00a0\u00d7\u00a0post\u2010surgical group &lt;0.0001). There were no statistical differences in total vaginal length measurements (\n                      <jats:italic>P<\/jats:italic>\n                      value post\u2010dilation\u00a0\u00d7\u00a0post\u2010surgical\u00a0=\u00a00.09) or Female Sexual Function Index scores (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a00.72) after both treatments.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Both treatments had satisfactory efficacy and positive outcomes for patients with vaginal agenesis concerning anatomical, functional, and sexual aspects, with minimum complications in the surgical group. Dilation treatment can remain the first\u2010line therapy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ijgo.13931","type":"journal-article","created":{"date-parts":[[2021,9,17]],"date-time":"2021-09-17T15:15:35Z","timestamp":1631891735000},"page":"574-581","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Treatment for vaginal agenesis: A prospective and comparative study between vaginal dilation and surgical neovaginoplasty"],"prefix":"10.1002","volume":"157","author":[{"given":"Vanessa R.","family":"Apfel","sequence":"first","affiliation":[{"name":"Urogynecology and Vaginal Surgery Sector Department of Gynecology Federal University of Sao Paulo  Sao Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia C.","family":"Takano","sequence":"additional","affiliation":[{"name":"Urogynecology and Vaginal Surgery Sector Department of Gynecology Federal University of Sao Paulo  Sao Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gisele V.","family":"Marquini","sequence":"additional","affiliation":[{"name":"Urogynecology and Vaginal Surgery Sector Department of Gynecology Federal University of Sao Paulo  Sao Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zsuzsanna I. K.","family":"de Jarmy di Bella","sequence":"additional","affiliation":[{"name":"Urogynecology and Vaginal Surgery Sector Department of Gynecology Federal University of Sao Paulo  Sao Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manoel J. B. C.","family":"Gir\u00e3o","sequence":"additional","affiliation":[{"name":"Urogynecology and Vaginal Surgery Sector Department of Gynecology Federal University of Sao Paulo  Sao Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marair G. F.","family":"Sartori","sequence":"additional","affiliation":[{"name":"Urogynecology and Vaginal Surgery Sector Department of Gynecology Federal University of Sao Paulo  Sao Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,10,4]]},"reference":[{"key":"e_1_2_9_2_1","first-page":"381","article-title":"Mayer\u2010Rokitansky\u2010Kuester syndrome. 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