{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T15:15:06Z","timestamp":1747149306725,"version":"3.40.5"},"reference-count":25,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,12,9]],"date-time":"2021-12-09T00:00:00Z","timestamp":1639008000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To identify risk factors associated with the occurrence of meconium aspiration syndrome (MAS) among neonates.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective case\u2010control study in a university affiliated tertiary medical center, including all neonates born with meconium stained amniotic fluid (MSAF) between March 2011 and March 2020. Patients were categorized by the occurrence of MAS. Demographic, pregnancy and delivery characteristics were compared between the two groups. Risk factors for MAS were analyzed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 90\u00a0579 singleton deliveries, a total of 11\u00a0856 with MSAF were included. Of these newborns, 78 (0.66%) were diagnosed with MAS Four factors were independently associated with MAS: delivery at &lt;38 0\/7\u00a0weeks (aOR [95% CI]: 3.48 (1.02\u201311.84), <jats:italic>P\u00a0<\/jats:italic>=\u00a00.046); higher body mass index (aOR [95% CI]: 1.09 (1.02\u20131.16), <jats:italic>P\u00a0<\/jats:italic>=\u00a00.003); lower amniotic fluid index (aOR [95% CI]: 0.99 (0.98\u20130.99), <jats:italic>P\u00a0<\/jats:italic>=\u00a00.032); higher white blood cell count (aOR [95% CI]: 1.11 (1.02\u20131.20), <jats:italic>P<\/jats:italic> = 0.009). The presence of one, two and three of the above\u2010mentioned risk factors yielded a risk for MAS of 0.8%, 2.5% and 100%, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>We identified independent risk factors for MAS and developed a risk score calculator. This tool may assist physicians in the management of deliveries complicated by MSAF.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ijgo.14034","type":"journal-article","created":{"date-parts":[[2021,11,19]],"date-time":"2021-11-19T07:27:18Z","timestamp":1637306838000},"page":"551-556","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Prediction of meconium aspiration syndrome by data available before delivery"],"prefix":"10.1002","volume":"158","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9594-5343","authenticated-orcid":false,"given":"Daphna","family":"Amitai Komem","sequence":"first","affiliation":[{"name":"The Department of Obstetrics and Gynecology The Chaim Sheba Medical Center  Ramat\u2010Gan Israel"},{"name":"The Faculty of Medicine Tel\u2010Aviv University  Tel\u2010Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raanan","family":"Meyer","sequence":"additional","affiliation":[{"name":"The Department of Obstetrics and Gynecology The Chaim Sheba Medical Center  Ramat\u2010Gan Israel"},{"name":"The Faculty of Medicine Tel\u2010Aviv University  Tel\u2010Aviv Israel"},{"name":"The Dr. Pinchas Bornstein Talpiot Medical Leadership Program, Sheba Medical Center, Tel Hashomer  Ramat\u2010Gan Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoav","family":"Yinon","sequence":"additional","affiliation":[{"name":"The Department of Obstetrics and Gynecology The Chaim Sheba Medical Center  Ramat\u2010Gan Israel"},{"name":"The Faculty of Medicine Tel\u2010Aviv University  Tel\u2010Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriel","family":"Levin","sequence":"additional","affiliation":[{"name":"The Department of Gynecologic Oncology Hadassah Medical Center Faculty of Medicine Hebrew University of Jerusalem  Jerusalem Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,12,9]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e3182117a26"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1017\/CBO9780511544774.033"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clp.2005.11.014"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/321545"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2005-2215"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471\u20100528.2011.03093.x"},{"key":"e_1_2_7_8_1","first-page":"1","article-title":"The risk of meconium aspiration syndrome (MAS) increases with gestational age at term","author":"Ward C","year":"2020","journal-title":"J Matern Fetal Neonatal Med"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0033-1361105"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1080\/14767058.2017.1410700"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.5468\/ogs.2015.58.1.24"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(02)01942-7"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2001.115120"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000002236"},{"issue":"5","key":"e_1_2_7_15_1","first-page":"311","article-title":"Birth weight standards in the live\u2010born population in Israel","volume":"7","author":"Dollberg S","year":"2005","journal-title":"Isr Med Assoc J"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006250-200107000-00005"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000001246"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1001648"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2015.01.028"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.5334\/aogh.2739"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jp.7200521"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0301-2115(98)00141-9"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(97)00308-6"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-020-05541-2"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1080\/14767058.2016.1236246"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006250-200610000-00048"}],"container-title":["International Journal of Gynecology &amp; 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