{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T19:50:42Z","timestamp":1775505042134,"version":"3.50.1"},"reference-count":21,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,12,5]],"date-time":"2021-12-05T00:00:00Z","timestamp":1638662400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate maternal and neonatal outcomes in pregnancies complicated by hypoglycemia on 100\u2010g oral glucose tolerance test (OGTT).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective cohort analysis of all live\u2010born deliveries in a single medical center during 2018 and 2019 with available OGTT results and birth outcomes. Preterm deliveries (&lt;34\u00a0weeks), multiple pregnancies and major anomalies were excluded. Hypoglycemia during OGTT was defined as at least one glucose value below 60\u00a0mg\/dl. Maternal characteristics and perinatal outcomes were compared between three groups: Hypoglycemia on OGTT, Normal OGTT and Abnormal OGTT. Univariate followed by multivariate analyses were used to control for confounders.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Overall, 2079 women were entered into the analysis. Of these, 216 (10.4%) had at least one hypoglycemic value, 1072 (51.6%) had normal OGTTs and 791 (38%) abnormal OGTTs. Hypoglycemia in OGTT was more prevalent in multiparous women and was associated with fetal male gender. Absolute birth weight, low birth weight and small for gestational age differed between groups; however, there was no difference between groups in overall birth weight centiles (60.1\u00a0\u00b1\u00a026.8 versus 63\u00a0\u00b1\u00a026 versus 60.9\u00a0\u00b1\u00a027; <jats:italic>P<\/jats:italic>\u00a0&gt;\u00a00.05). Following adjustment of confounders, hypoglycemia was not associated with rates of low birth weight or small for gestational age (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.05). There were no other differences in perinatal outcomes between groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Hypoglycemia in OGTT is not associated with maternal or neonatal adverse outcomes.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ijgo.14037","type":"journal-article","created":{"date-parts":[[2021,11,19]],"date-time":"2021-11-19T07:27:18Z","timestamp":1637306838000},"page":"585-591","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Hypoglycemia during the oral glucose tolerance test in pregnancy\u2014maternal characteristics and neonatal outcomes"],"prefix":"10.1002","volume":"158","author":[{"given":"Shira","family":"Raviv","sequence":"first","affiliation":[{"name":"Hillel Yaffe Medical Center  Hadera Israel"},{"name":"The Rappaport Faculty of Medicine Technion  Haifa Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Renana","family":"Wilkof\u2010Segev","sequence":"additional","affiliation":[{"name":"Hillel Yaffe Medical Center  Hadera Israel"},{"name":"The Rappaport Faculty of Medicine Technion  Haifa Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Esther","family":"Maor\u2010Sagie","sequence":"additional","affiliation":[{"name":"Hillel Yaffe Medical Center  Hadera Israel"},{"name":"The Rappaport Faculty of Medicine Technion  Haifa Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amir","family":"Naeh","sequence":"additional","affiliation":[{"name":"Hillel Yaffe Medical Center  Hadera Israel"},{"name":"The Rappaport Faculty of Medicine Technion  Haifa Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yochai","family":"Yoeli","sequence":"additional","affiliation":[{"name":"Hillel Yaffe Medical Center  Hadera Israel"},{"name":"The Rappaport Faculty of Medicine Technion  Haifa Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mordechai","family":"Hallak","sequence":"additional","affiliation":[{"name":"Hillel Yaffe Medical Center  Hadera Israel"},{"name":"The Rappaport Faculty of Medicine Technion  Haifa Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6887-6314","authenticated-orcid":false,"given":"Rinat","family":"Gabbay\u2010Benziv","sequence":"additional","affiliation":[{"name":"Hillel Yaffe Medical Center  Hadera Israel"},{"name":"The Rappaport Faculty of Medicine Technion  Haifa Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,12,5]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000002501"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.7326\/M13-2905"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(82)90349-0"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.2337\/diab.28.12.1039"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2016.04.040"},{"issue":"5","key":"e_1_2_8_7_1","first-page":"337","article-title":"Postprandial reactive hypoglycemia","volume":"26","author":"Brun JF","year":"2000","journal-title":"Diabetes Metab"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.4158\/EP13132.RA"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.5603\/GP.a2018.0005"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabres.2018.11.018"},{"issue":"5","key":"e_1_2_8_11_1","first-page":"311","article-title":"Birth weight standards in the live\u2010born population in Israel","volume":"7","author":"Dollberg S","year":"2005","journal-title":"Isr Med Assoc J"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(91)90012-G"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1447-0756.2012.02009.x"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(99)70662-9"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(90)91306-W"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.2478\/amb-2014-0002"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2020.03.033"},{"key":"e_1_2_8_18_1","first-page":"S1","article-title":"Islet cell dysfunction in progression to diabetes mellitus","volume":"107","author":"Spellman CW","year":"2007","journal-title":"J Am Osteopath Assoc"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12020-016-1202-4"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jogoh.2020.101703"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000159577.28448.f9"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/jog.12794"}],"container-title":["International Journal of Gynecology &amp; Obstetrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijgo.14037","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ijgo.14037","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijgo.14037","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,20]],"date-time":"2023-08-20T08:58:40Z","timestamp":1692521920000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/ijgo.14037"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12,5]]},"references-count":21,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022,9]]}},"alternative-id":["10.1002\/ijgo.14037"],"URL":"https:\/\/doi.org\/10.1002\/ijgo.14037","archive":["Portico"],"relation":{},"ISSN":["0020-7292","1879-3479"],"issn-type":[{"value":"0020-7292","type":"print"},{"value":"1879-3479","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,12,5]]},"assertion":[{"value":"2021-06-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-11-17","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-12-05","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}