{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T15:12:26Z","timestamp":1747149146930,"version":"3.40.5"},"reference-count":16,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2022,3,18]],"date-time":"2022-03-18T00:00:00Z","timestamp":1647561600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100007194","name":"Wenzhou Municipal Science and Technology Bureau","doi-asserted-by":"publisher","award":["Y20180021"],"award-info":[{"award-number":["Y20180021"]}],"id":[{"id":"10.13039\/501100007194","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To investigate the feasibility of switching from in vitro fertilization (IVF) to in vitro maturation (IVM) combined with all\u2010blastocyst\u2010culture and transfer as a supplementary infertility treatment in patients with ovarian hyperstimulation syndrome (OHSS) tendency<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Retrospective cohort study including 184 patients who switched from IVF and underwent 192 IVM cycles between January 2016 and December 2020. The outcomes were compared between cleavage\u2010stage embryo transfer (group A, <jats:italic>n\u00a0=<\/jats:italic>\u00a074) and blastocyst\u2010stage transfer (group B, <jats:italic>n\u00a0=<\/jats:italic>\u00a052) groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The OHSS rate is 0%. 66\u00a0cycles were canceled for transfer. Among the 126 transfer cycles, number of retrieved oocytes, proportion of metaphase II oocytes, cleavage rate, and proportion of high\u2010quality embryos on day 3 post\u2010fertilization are significantly lower in group A than that in group B. On the contrary, number of transferred embryos is significantly lower in group B than that in group A, whereas the rates of implantation, clinical pregnancy, and live births are significantly higher in group B than that in group A.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Timely switching to IVM combined with all\u2010blastocyst\u2010culture and transfer for patients undergoing controlled ovarian hyperstimulation and exhibiting characteristics of OHSS tendency is feasible as a supplementary infertility treatment.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ijgo.14160","type":"journal-article","created":{"date-parts":[[2022,2,25]],"date-time":"2022-02-25T11:25:00Z","timestamp":1645788300000},"page":"487-494","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["The feasibility of switching from <scp>IVF<\/scp> to <scp>IVM<\/scp> combined with all\u2010blastocyst\u2010culture and transfer for patients with ovarian hyperstimulation syndrome tendency"],"prefix":"10.1002","volume":"159","author":[{"given":"Fanxuan","family":"Zhao","sequence":"first","affiliation":[{"name":"Reproductive Medical Center The Second Affiliated Hospital of Wenzhou Medical College and Yuying Children's Hospital  Wenzhou China"},{"name":"Key Laboratory of Reproductive Dysfunction Management of Zhejiang Province, Assisted Reproduction Unit, Department of Obstetrics and Gynecology, Sir Run Run Shaw Hospital School of Medicine  Hangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaosheng","family":"Lu","sequence":"additional","affiliation":[{"name":"Reproductive Medical Center The Second Affiliated Hospital of Wenzhou Medical College and Yuying Children's Hospital  Wenzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chaochao","family":"Gong","sequence":"additional","affiliation":[{"name":"Reproductive Medical Center The Second Affiliated Hospital of Wenzhou Medical College and Yuying Children's Hospital  Wenzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haitao","family":"Xi","sequence":"additional","affiliation":[{"name":"Reproductive Medical Center The Second Affiliated Hospital of Wenzhou Medical College and Yuying Children's Hospital  Wenzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoming","family":"Liu","sequence":"additional","affiliation":[{"name":"Reproductive Medical Center The Second Affiliated Hospital of Wenzhou Medical College and Yuying Children's Hospital  Wenzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2385-205X","authenticated-orcid":false,"given":"Junzhao","family":"Zhao","sequence":"additional","affiliation":[{"name":"Reproductive Medical Center The Second Affiliated Hospital of Wenzhou Medical College and Yuying Children's Hospital  Wenzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,3,18]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2014.03.030"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD001750.pub4"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12020-015-0744-1"},{"key":"e_1_2_8_5_1","first-page":"924","article-title":"Clinical study on in vitro maturation of immature oocytes transferred from conventional in vitro fertilization","volume":"44","author":"Wang PY","year":"2009","journal-title":"Zhonghua Fu Chan Ke Za Zhi"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2018.09.011"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/deh487"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/der037"},{"key":"e_1_2_8_9_1","first-page":"378","article-title":"In vitro culture of human blastocyst","author":"Gardner DK","year":"1999","journal-title":"Towar Reprod Certain Infertil Genet Beyond"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.14684"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/8.3.291"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2009.10.034"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2012.04.046"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2014.05.013"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000284627.38540.80"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10815-013-9945-9"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2014.12.096"}],"container-title":["International Journal of Gynecology &amp; 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