{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T14:36:25Z","timestamp":1793889385952,"version":"4.8.0"},"reference-count":19,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,3,29]],"date-time":"2022-03-29T00:00:00Z","timestamp":1648512000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2022,3,29]],"date-time":"2022-03-29T00:00:00Z","timestamp":1648512000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp;amp; Obste"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    To evaluate left ventricular function and measure N\u2010terminal pro B\u2010type natriuretic peptide (NT\u2010proBNP) levels in women with hypertensive disorders of pregnancy (HDP) in comparison to normotensive women and correlate these with maternal and neonatal outcomes. This was a prospective observational case\u2013control study from 2018 to 2020 in an Indian tertiary care hospital and included antenatal women beyond 20\u2009weeks of pregnancy with 160 women with HDP as cases and 160 normotensive women as controls. Echocardiography was performed to assess left ventricular structure and function. Quantitative analysis of NT\u2010proBNP levels was performed based on fluorescence immunochromatography. Women with HDP were observed to have a significant difference in the value of left ventricular structure and function (\n                    <jats:italic>P<\/jats:italic>\n                    \u00a0&lt;\u20090.001). Mild systolic dysfunction was found in 13 (8.1%) women in the HDP group 8 (20%) women with severe pre\u2010eclampsia and 5 (33.3%) women with eclampsia). Significantly lower values of left ventricular ejection fraction and higher values of NT\u2010proBNP were recorded in women with HDP who developed maternal complications and had adverse neonatal outcomes (\n                    <jats:italic>P<\/jats:italic>\n                    \u00a0&lt;\u20090.001). Echocardiography and NT\u2010proBNP levels have been shown to have a significant role in women with severe forms of HDP to detect early signs of cardiac dysfunction.\n                  <\/jats:p>","DOI":"10.1002\/ijgo.14182","type":"journal-article","created":{"date-parts":[[2022,3,19]],"date-time":"2022-03-19T03:54:16Z","timestamp":1647662056000},"page":"764-770","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Left ventricular function and N\u2010terminal pro b\u2010type natriuretic peptide levels in women with hypertensive disorders of pregnancy: A prospective observational study"],"prefix":"10.1002","volume":"159","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8888-0601","authenticated-orcid":false,"given":"Shivani","family":"Verma","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Safdarjung Hospital  Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sunita","family":"Malik","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Safdarjung Hospital  Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandeep","family":"Bansal","sequence":"additional","affiliation":[{"name":"Department of Cardiology Safdarjung Hospital  Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,3,29]]},"reference":[{"key":"e_1_2_9_2_1","first-page":"728","volume-title":"Williams Obstetrics","author":"Cunningham FG","year":"2018"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2393-10-12"},{"key":"e_1_2_9_4_1","first-page":"357","article-title":"Risk factors for severe preeclampsia","volume":"83","author":"Stone JL","year":"1994","journal-title":"Obstet Gynecol"},{"key":"e_1_2_9_5_1","unstructured":"National Health Portal Government of India:https:\/\/www.nhp.gov.in\/disease\/gynaecologyand\u2010obstetrics\/preeclampsia. Accessed on August 18 2021."},{"key":"e_1_2_9_6_1","first-page":"163","article-title":"Incidence of pregnancy\u2010induced hypertension and prescription pattern of antihypertensive drugs in pregnancy","volume":"4","author":"Sajith M","year":"2014","journal-title":"IJPSR"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.semperi.2011.09.011"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1701-2163(15)30588-0"},{"key":"e_1_2_9_9_1","first-page":"46","volume-title":"Williams Obstetrics","author":"Cunningham FG","year":"2018"},{"key":"e_1_2_9_10_1","first-page":"459","article-title":"Left ventricular function of patients with pregnancy\u2010induced hypertension evaluated using velocity vector imaging echocardiography and N\u2010terminal pro\u2010brain natriuretic peptide","volume":"5","author":"Li Y","year":"2018","journal-title":"Echocardiography"},{"key":"e_1_2_9_11_1","first-page":"QC01","article-title":"Maternal cardiac diastolic dysfunction by doppler echocardiography in women with preeclampsia","volume":"10","author":"Muthyala T","year":"2016","journal-title":"J Clin Diagn Res"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.4103\/2211-4122.187961"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.18203\/2320-1770.ijrcog20174996"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.5830\/CVJA-2013-023"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00966.2001"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.5830\/CVJA-2017-031"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2004.07.034"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2018.04.048"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.preghy.2012.04.224"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40119-021-00230-w"}],"container-title":["International Journal of Gynecology &amp; Obstetrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijgo.14182","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ijgo.14182","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijgo.14182","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T14:07:04Z","timestamp":1793887624000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/ijgo.14182"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3,29]]},"references-count":19,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022,12]]}},"alternative-id":["10.1002\/ijgo.14182"],"URL":"https:\/\/doi.org\/10.1002\/ijgo.14182","archive":["Portico"],"relation":{},"ISSN":["0020-7292","1879-3479"],"issn-type":[{"value":"0020-7292","type":"print"},{"value":"1879-3479","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,3,29]]},"assertion":[{"value":"2021-10-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-03-16","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-03-29","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}