{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T00:29:00Z","timestamp":1788481740171,"version":"build-2803163510"},"reference-count":25,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,5,2]],"date-time":"2022-05-02T00:00:00Z","timestamp":1651449600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology & Obste"],"published-print":{"date-parts":[[2022,12]]},"abstract":"Abstract<\/jats:title>\n \n Objective<\/jats:title>\n To study the outcome of pregnancies with first\u2010trimester increased nuchal translucency and cystic hygromas.<\/jats:p>\n <\/jats:sec>\n \n Methodology<\/jats:title>\n Retrospective study of 132 pregnancies with first\u2010trimester increased nuchal translucency and cystic hygromas, between January 2015 to December 2018 at Corniche Hospital, Abu Dhabi, UAE. Fetal karyotyping, detailed ultrasound at 18\u201322\u2009weeks and fetal echocardiography were offered to all women. Adverse outcomes included miscarriage, intrauterine fetal death, termination of pregnancy, neonatal death and structural abnormalities.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n Of the 132 pregnancies, 13 had NT\u2009>\u200995th percentile, 89 had NT \u22653\u2009mm and 30 had cystic hygroma. Among 13 pregnancies with NT\u2009>\u200995th centile, 7.6% had abnormal karyotype. Among 89 pregnancies with NT \u22653\u2009mm, 29.2% had abnormal karyotype, 13.4% miscarriage, 7.8% underwent TOP, 5.6% intrauterine fetal death, 1.1% neonatal death and 14.6% had structural abnormalities. Among 30 pregnancies with cystic hygroma, 40% had abnormal karyotype, 20% miscarriage, 13.3% TOP, 13.3% intrauterine fetal death, 6.6% had neonatal death and 20% had structural abnormalities.<\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n In our study, karyotype abnormalities increased with increasing nuchal translucency with highest risk in fetuses with cystic hygromas. Increased nuchal translucency was associated with adverse pregnancy outcome, which was higher in the group with NT\u22656\u2009mm and cystic hygromas.<\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/ijgo.14222","type":"journal-article","created":{"date-parts":[[2022,4,18]],"date-time":"2022-04-18T05:06:28Z","timestamp":1650258388000},"page":"841-849","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Outcome of pregnancies with first\u2010trimester increased nuchal translucency and cystic hygroma in a tertiary maternity hospital in United Arab Emirates"],"prefix":"10.1002","volume":"159","author":[{"given":"Sumalatha","family":"Narava","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Corniche Hospital Abu Dhabi United Arab Emirates"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sushma","family":"Balbir Singh","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Corniche Hospital Abu Dhabi United Arab Emirates"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samikshyamani","family":"Barpanda","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Corniche Hospital Abu Dhabi United Arab Emirates"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leanne","family":"Bricker","sequence":"additional","affiliation":[{"name":"Fetal Medicine Department Corniche Hospital Abu Dhabi United Arab Emirates"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,5,2]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.10059"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2004.03.090"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1080\/00016340701644843"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40477-017-0251-8"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e318264f829"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.308"},{"key":"e_1_2_10_8_1","unstructured":"Fetal Medicine Foundation.The 11\u201313\u2009weeks scan [FMF website].www.fetalmedicine.com\/fmf\/online\u2010education\/01\u201011\u2010136\u2010week\u2010scan. Accessed April 2019."},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2004.12.093"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.1831"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000191301.63871.c6"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.17421"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1080\/14767058.2019.1569622"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/aogs.13877"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.2147\/IJGM.S330960"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.3346\/jkms.2004.19.1.32"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1017\/s0021932097004914"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.4044"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10038-008-0299-6"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.17352\/ojbs.000013"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.4143"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1177\/0969141315595826"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.1985"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1017\/S1047951109990655"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.321"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1097\/GIM.0b013e318217477f"}],"container-title":["International Journal of Gynecology & Obstetrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijgo.14222","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ijgo.14222","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijgo.14222","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,19]],"date-time":"2023-08-19T05:50:26Z","timestamp":1692424226000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/ijgo.14222"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5,2]]},"references-count":25,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022,12]]}},"alternative-id":["10.1002\/ijgo.14222"],"URL":"https:\/\/doi.org\/10.1002\/ijgo.14222","archive":["Portico"],"relation":{},"ISSN":["0020-7292","1879-3479"],"issn-type":[{"value":"0020-7292","type":"print"},{"value":"1879-3479","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,5,2]]},"assertion":[{"value":"2021-07-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-04-11","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-05-02","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}