{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,25]],"date-time":"2025-07-25T10:11:24Z","timestamp":1753438284937},"reference-count":24,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,6,5]],"date-time":"2022-06-05T00:00:00Z","timestamp":1654387200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100009601","name":"Beijing Municipal Administration of Hospitals","doi-asserted-by":"publisher","award":["PX2019053"],"award-info":[{"award-number":["PX2019053"]}],"id":[{"id":"10.13039\/501100009601","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate the effectiveness of bromocriptine for prevention of ovarian hyperstimulation syndrome (OHSS).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The retrospective study included women at risk of OHSS who were receiving gonadotropin\u2010releasing hormone antagonist protocols, including 52 women given 2.5\u00a0mg bromocriptine by rectal insertion, 52 women given 500\u2009ml intravenous hydroxyethyl starch (HES), and 40 women who received no intervention. Treatments were administered daily for 5\u2009days beginning on the day of oocyte retrieval. Baseline information and data related to OHSS were compared.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>No significant differences were found among groups in estradiol concentration on the day of trigger or in number of retrieved oocytes. Incidence of mild OHSS was not significantly different among groups, respectively 13.5%, 15.4%, and 17.5% (<jats:italic>P<\/jats:italic>\u00a0&gt;\u20090.05). The incidence of moderate to severe OHSS was significantly lower in the bromocriptine and HES groups compared with the control group, respectively 7.7%, 5.8%, and 22.5% (<jats:italic>P<\/jats:italic>\u00a0&lt;\u20090.05). D\u2010dimer levels were significantly lower in the bromocriptine and HES groups compared with the control group on Day 5 after oocyte retrieval (<jats:italic>P<\/jats:italic>\u00a0&lt;\u20090.05). No differences in liver or renal function were found in the three groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Bromocriptine was apparently as effective as intravenous HES in patients with high risk of OHSS.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ijgo.14264","type":"journal-article","created":{"date-parts":[[2022,5,16]],"date-time":"2022-05-16T09:55:35Z","timestamp":1652694935000},"page":"944-950","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Comparison of bromocriptine and hydroxyethyl starch in the prevention of ovarian hyperstimulation syndrome"],"prefix":"10.1002","volume":"159","author":[{"given":"Qiaoli","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Human Reproductive Medicine, Beijing Obstetrics and Gynecology Hospital Capital Medical University. Beijing Maternal and Child Health Care Hospital  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanmin","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Human Reproductive Medicine, Beijing Obstetrics and Gynecology Hospital Capital Medical University. Beijing Maternal and Child Health Care Hospital  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaomeng","family":"Bu","sequence":"additional","affiliation":[{"name":"Department of Human Reproductive Medicine, Beijing Obstetrics and Gynecology Hospital Capital Medical University. Beijing Maternal and Child Health Care Hospital  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chanwei","family":"Jia","sequence":"additional","affiliation":[{"name":"Department of Human Reproductive Medicine, Beijing Obstetrics and Gynecology Hospital Capital Medical University. Beijing Maternal and Child Health Care Hospital  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanjun","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Human Reproductive Medicine, Beijing Obstetrics and Gynecology Hospital Capital Medical University. Beijing Maternal and Child Health Care Hospital  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuyu","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Human Reproductive Medicine, Beijing Obstetrics and Gynecology Hospital Capital Medical University. Beijing Maternal and Child Health Care Hospital  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,6,5]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmn008"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2009.02.049"},{"issue":"1","key":"e_1_2_10_4_1","article-title":"Interventions for the prevention of OHSS in ART cycles: an overview of Cochrane reviews","volume":"2017","author":"Mourad S","year":"2017","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10815-010-9387-6"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmq006"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0049-3848(17)30070-1"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0301-2115(00)00452-8"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2010.03.028"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(00)00492-1"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/12.12.2599"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2005.07.1292"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7827-10-32"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2009.01.085"},{"key":"e_1_2_10_15_1","article-title":"Volume expanders for the prevention of ovarian hyperstimulation syndrome","volume":"31","author":"Youssef MA","year":"2016","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2014.09.046"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12958-015-0102-4"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2006-0657"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.3109\/09513590.2012.736554"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2011.04.017"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2011.02.032"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-198005000-00007"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.14684"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2005.10.005"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11102-013-0524-y"}],"container-title":["International Journal of Gynecology &amp; Obstetrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijgo.14264","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ijgo.14264","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijgo.14264","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,19]],"date-time":"2023-08-19T09:51:03Z","timestamp":1692438663000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/ijgo.14264"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6,5]]},"references-count":24,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022,12]]}},"alternative-id":["10.1002\/ijgo.14264"],"URL":"https:\/\/doi.org\/10.1002\/ijgo.14264","archive":["Portico"],"relation":{},"ISSN":["0020-7292","1879-3479"],"issn-type":[{"value":"0020-7292","type":"print"},{"value":"1879-3479","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,6,5]]},"assertion":[{"value":"2021-11-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-05-09","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-06-05","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}