{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T15:12:47Z","timestamp":1747149167000,"version":"3.40.5"},"reference-count":29,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2022,8,3]],"date-time":"2022-08-03T00:00:00Z","timestamp":1659484800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2023,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To assess the efficacy of ovulation induction and intrauterine insemination (IUI) in couples with diminished ovarian reserve (DOR).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Women aged 20\u201339\u2009years and men younger than 50\u2009years were included. Four \u201covarian reserve groups\u201d were created according to anti\u2010M\u00fcllerian hormone (AMH) and the partner's age. Gestational sac finding on ultrasound examination was the primary outcome measure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The study was carried out on a total of 770\u2009cycles of 362 women in an infertility cohort that consisted of 75 women with DOR treated by 153\u2009cycles and 287 women without DOR treated by 617\u2009cycles. The pregnancy rate was similar in the four ovarian reserve groups in terms of first, second, third plus fourth, and total attempts of IUI cycles. Moreover, the pregnancy rate, miscarriage rate, and multiple pregnancy rate were similar. We found no difference in the cumulative pregnancy rate among the groups after four IUI cycles. Multivariate logistic regression analysis of the entire cohort revealed that infertility duration, post\u2010wash sperm count, and follicle number greater than 11\u2009mm on the day of human chorionic gonadotropin trigger were independent predictors of pregnancy (<jats:italic>P<\/jats:italic>\u00a0&lt;\u20090.001). Neither age nor AMH predicted pregnancy after ovulation stimulation and IUI.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Ovulation stimulation and IUI are equally effective in women with DOR and in women with normal ovarian reserve in terms of pregnancy rate, multiple pregnancy rate, and miscarriage rate per IUI cycle or cumulative pregnancy rate after four cycles of IUI.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ijgo.14325","type":"journal-article","created":{"date-parts":[[2022,7,3]],"date-time":"2022-07-03T13:04:07Z","timestamp":1656853447000},"page":"620-627","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Evaluating the efficacy of ovulation stimulation with intrauterine insemination in women with diminished ovarian reserve compared to women with normal ovarian reserve"],"prefix":"10.1002","volume":"160","author":[{"given":"Semih","family":"Kaleli","sequence":"first","affiliation":[{"name":"Istanbul \u00dcniversitesi\u2010Cerrahpa\u015fa, Cerrahpa\u015fa Faculty of Medicine, Department of Obstetrics and Gynecology, Reproductive Endocrinology and Assisted Reproduction Unit  \u0130stanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehmet E.","family":"Kervanc\u0131o\u011flu","sequence":"additional","affiliation":[{"name":"Istanbul \u00dcniversitesi\u2010Cerrahpa\u015fa, Cerrahpa\u015fa Faculty of Medicine, Department of Obstetrics and Gynecology, Reproductive Endocrinology and Assisted Reproduction Unit  \u0130stanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naciye","family":"Erol","sequence":"additional","affiliation":[{"name":"Istanbul \u00dcniversitesi\u2010Cerrahpa\u015fa, Cerrahpa\u015fa Faculty of Medicine, Department of Obstetrics and Gynecology, Reproductive Endocrinology and Assisted Reproduction Unit  \u0130stanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulviyya","family":"Alakbarova","sequence":"additional","affiliation":[{"name":"Istanbul \u00dcniversitesi\u2010Cerrahpa\u015fa, Cerrahpa\u015fa Faculty of Medicine, Department of Obstetrics and Gynecology, Reproductive Endocrinology and Assisted Reproduction Unit  \u0130stanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6982-6324","authenticated-orcid":false,"given":"Elif","family":"Ak\u015fahin","sequence":"additional","affiliation":[{"name":"Istanbul \u00dcniversitesi\u2010Cerrahpa\u015fa, Cerrahpa\u015fa Faculty of Medicine, Department of Obstetrics and Gynecology, Reproductive Endocrinology and Assisted Reproduction Unit  \u0130stanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u0130smail F.","family":"\u00d6\u00e7er","sequence":"additional","affiliation":[{"name":"Istanbul \u00dcniversitesi\u2010Cerrahpa\u015fa, Cerrahpa\u015fa Faculty of Medicine, Department of Obstetrics and Gynecology, Reproductive Endocrinology and Assisted Reproduction Unit  \u0130stanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,8,3]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2020.09.134"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.humrep.a019422"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.2006.02533.x"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.3109\/01443615.2014.935718"},{"key":"e_1_2_8_6_1","first-page":"602","article-title":"Anti\u2010Mullerian hormone as a predictor of IVF outcome","volume":"14","author":"Lekamge DN","year":"2007","journal-title":"RBM 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