{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:45:33Z","timestamp":1786977933767,"version":"build-2736575974"},"reference-count":25,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2022,7,27]],"date-time":"2022-07-27T00:00:00Z","timestamp":1658880000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2023,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>\n                      To compare perinatal outcomes in pregnancies with fetal growth restriction (FGR) undergoing induction of labor by extra\u2010amniotic balloon (EAB) versus prostaglandin E\n                      <jats:sub>2<\/jats:sub>\n                      (PGE\n                      <jats:sub>2<\/jats:sub>\n                      ).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      A retrospective cohort study of women with singleton pregnancies and FGR, undergoing induction at term via EAB, PGE\n                      <jats:sub>2<\/jats:sub>\n                      , or both, at a single medical center (2014\u20132017). Primary outcome was rate of cesarean deliveries (CDs). Secondary outcomes included composite maternal and neonatal outcomes.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Overall, 266 women met the inclusion criteria. Among them, 131 (49.2%) underwent induction by PGE\n                      <jats:sub>2<\/jats:sub>\n                      , 116 (43.6%) by EAB, and 19 (7.14%) by both methods. No differences were noted in baseline characteristics. Rate of CD (17.24% vs. 6.11% vs. 10.53%,\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u20090.022) and maternal composite outcome (18.97% vs. 6.11% vs. 10.53%,\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u20090.01) were higher among women who underwent induction by EAB compared with PGE\n                      <jats:sub>2<\/jats:sub>\n                      or both. No difference was noted between groups in neonatal outcomes. In a multivariable logistic regression, rates of cesarean delivery and composite maternal outcome were no longer higher in the EAB group (adjusted odds ratio [aOR] 1.68, 95% confidence interval [CI] 0.68\u20134.16,\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u20090.260; and aOR 1.94, 95% CI 0.84\u20134.45,\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u20090.120, respectively).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      EAB and PGE\n                      <jats:sub>2<\/jats:sub>\n                      have comparable maternal and neonatal outcomes when used for induction of labor due to FGR.\n                    <\/jats:p>\n                  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