{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T19:29:17Z","timestamp":1789932557116,"version":"4.0.1"},"reference-count":20,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,9,29]],"date-time":"2022-09-29T00:00:00Z","timestamp":1664409600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100010414","name":"Health Research Board","doi-asserted-by":"publisher","award":["CHY240"],"award-info":[{"award-number":["CHY240"]}],"id":[{"id":"10.13039\/100010414","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To describe the growth dynamics of fetuses with initial fetal growth restriction (FGR) later outgrowing the 10th centile for estimated fetal weight with respect to perinatal outcomes and maternal factors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A multicenter prospective study recruited 1116 patients for ultrasound surveillance between 2010 and 2012. All pregnancies were growth\u2010restricted singleton gestations between 24\u2009+\u00a00 and 36\u2009+\u00a00\u2009weeks. Biometry and Doppler analysis were carried out, and delivery and adverse perinatal outcomes were recorded.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 193 (17%) fetuses outgrew their diagnosis of initial FGR (surpassed the 10th centile) on their last sonogram before delivery. These fetuses were termed \u201cgrowers,\u201d to compare with the true FGR group. The mothers of \u201cgrowers\u201d were less likely to be smokers (14% vs 25%, <jats:italic>P<\/jats:italic>\u00a0=\u20090.0001) or affected by hypertensive pregnancy complications (5.2% vs 15%, <jats:italic>P<\/jats:italic>\u00a0=\u20090.001). Of the growers, 49 (25%) had an abnormal umbilical artery Doppler; however, in most cases (33\/49, 67%), this was a single episode of raised umbilical artery pulsatility index, which subsequently normalized.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>There were dynamic growth changes in FGR fetuses, with 17% outgrowing their original diagnosis. Positive growth spurts more commonly occurred in healthy mothers. Once a fetus had outgrown the 10th centile, antenatal surveillance could be decreased.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ijgo.14470","type":"journal-article","created":{"date-parts":[[2022,9,21]],"date-time":"2022-09-21T13:38:41Z","timestamp":1663767521000},"page":"198-203","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Dynamic growth changes in fetal growth restriction using serial ultrasonographic biometry and umbilical artery doppler: The multicenter <scp>PORTO<\/scp> study"],"prefix":"10.1002","volume":"161","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3615-2618","authenticated-orcid":false,"given":"Fiona","family":"Cody","sequence":"first","affiliation":[{"name":"Rotunda Hospital  Dublin Ireland"},{"name":"Royal College of Surgeons in Ireland  Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia","family":"Unterscheider","sequence":"additional","affiliation":[{"name":"Royal Women's Hospital  Victoria Australia"},{"name":"University of Melbourne  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sean","family":"Daly","sequence":"additional","affiliation":[{"name":"Coombe Women and Infants University Hospital  Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Geary","sequence":"additional","affiliation":[{"name":"Rotunda Hospital  Dublin Ireland"},{"name":"Royal College of Surgeons in Ireland  Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mairead","family":"Kennelly","sequence":"additional","affiliation":[{"name":"UCD Center for Human Reproduction Coombe Women and Infants University Hospital  Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fionnuala","family":"McAuliffe","sequence":"additional","affiliation":[{"name":"UCD Obstetrics and Gynecology, School of Medicine and Medical Science, National Maternity Hospital  Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Morrison","sequence":"additional","affiliation":[{"name":"National University of Ireland  Galway Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keelin","family":"O'Donoghue","sequence":"additional","affiliation":[{"name":"University College Cork Cork University Maternity Hospital  Cork Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alyson","family":"Hunter","sequence":"additional","affiliation":[{"name":"Royal Jubilee Maternity Hospital  Belfast Ireland"},{"name":"Graduate Entry Medical School University of Limerick  Limerick Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Dicker","sequence":"additional","affiliation":[{"name":"Royal College of Surgeons in Ireland  Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth","family":"Tully","sequence":"additional","affiliation":[{"name":"Royal College of Surgeons in Ireland  Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel","family":"Fhearaigh","sequence":"additional","affiliation":[{"name":"Royal College of Surgeons in Ireland  Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fergal","family":"Malone","sequence":"additional","affiliation":[{"name":"Rotunda Hospital  Dublin Ireland"},{"name":"Royal College of Surgeons in Ireland  Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"for the Perinatal Ireland Research Consortium","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,9,29]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijgo.13522"},{"key":"e_1_2_10_3_1","unstructured":"Small\u2010For\u2010Gestational\u2010Age Fetus Investigation and Management (Green\u2010Top Guideline No. 31). Royal College of Obstetricians & Gynecologists 2013 www.rcog.org.uk\/en\/guidelines\u2010research\u2010services\/guidelines\/gtg31\/. Accessed 11 Feb. 2022."},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2013.02.007"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(85)90298-4"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.4137\/cmped.s40070"},{"issue":"420","key":"e_1_2_10_7_1","first-page":"e1","article-title":"Defining the residual risk of adverse perinatal outcome in growth\u2010restricted fetuses with normal umbilical artery blood flow","volume":"211","author":"O'Dwyer V","year":"2014","journal-title":"Am J Obstet Gynecol"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2013.03.011"},{"issue":"2","key":"e_1_2_10_9_1","first-page":"150","article-title":"Growth assessment in diagnosis of Fetal Growth Restriction. 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