{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,28]],"date-time":"2025-11-28T12:33:05Z","timestamp":1764333185168,"version":"3.40.5"},"reference-count":18,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2022,10,10]],"date-time":"2022-10-10T00:00:00Z","timestamp":1665360000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2023,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To compare the efficacy of using a combination of transcervical Foley catheter and sublingual misoprostol with sublingual misoprostol alone for induction of labor (IOL) in women with pre\u2010eclampsia between 28 and 34\u2009weeks of pregnancy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This randomized controlled trial was conducted on women with pre\u2010eclampsia at 28\u201334\u2009weeks of pregnancy, with unfavorable cervix, admitted to a tertiary hospital in south India. They were randomized to receive either a combination of transcervical Foley catheter and sublingual misoprostol, or sublingual misoprostol alone. Vaginal birth within 24\u2009h of induction, induction to delivery interval, and neonatal morbidity\/mortality were the main outcome measures.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Vaginal birth within 24\u2009h was higher with the combination of Foley catheter and sublingual misoprostol compared with sublingual misoprostol alone (60% versus 41.4%, <jats:italic>P<\/jats:italic>\u00a0=\u00a00.028). Overall vaginal delivery rates were comparable between the groups (90% versus 80%, <jats:italic>P<\/jats:italic>\u00a0=\u00a00.051). There was no difference in number of doses of misoprostol, and induction to delivery interval between groups. After excluding those with lower likelihood of neonatal survival, live birth rates, mean birth weight, and neonatal intensive care unit admission rates were similar in both groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Combination of transcervical Foley catheter and sublingual misoprostol was found to be more effective in achieving vaginal birth within 24\u2009h compared with sublingual misoprostol for IOL in pre\u2010eclampsia between 28 and 34\u2009weeks of pregnancy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Trial Registration Number<\/jats:title><jats:p>CTRI\/2018\/09\/015766; http:\/\/ctri.nic.in\/Clinicaltrials\/pmaindet2.php?trialid=27984.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ijgo.14477","type":"journal-article","created":{"date-parts":[[2022,9,24]],"date-time":"2022-09-24T12:43:50Z","timestamp":1664023430000},"page":"432-438","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Efficacy of combination of transcervical Foley catheter and sublingual misoprostol versus sublingual misoprostol for labor induction in pre\u2010eclampsia at 28\u201334\u2009weeks"],"prefix":"10.1002","volume":"161","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9605-3769","authenticated-orcid":false,"given":"Jyotsna","family":"Sharma","sequence":"first","affiliation":[{"name":"Department of Obstetrics &amp; Gynecology Jawaharlal Institute of Post\u2010graduate Medical Education &amp; Research (JIPMER)  Puducherry India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1372-7634","authenticated-orcid":false,"given":"Haritha","family":"Sagili","sequence":"additional","affiliation":[{"name":"Department of Obstetrics &amp; Gynecology Jawaharlal Institute of Post\u2010graduate Medical Education &amp; Research (JIPMER)  Puducherry India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4881-0382","authenticated-orcid":false,"given":"Anish","family":"Keepanasseril","sequence":"additional","affiliation":[{"name":"Department of Obstetrics &amp; Gynecology Jawaharlal Institute of Post\u2010graduate Medical Education &amp; Research (JIPMER)  Puducherry India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,10,10]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2214-109X(14)70227-X"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(15)00838-7"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1155\/2011\/214365"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.117.10803"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(17)31367-3"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2015.01.005"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph17061825"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000437382.03963.88"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12098-020-03456-z"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1080\/01443615.2017.1351931"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.16319"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2006.04.031"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000001778"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/jp.2016.183"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2393-14-308"},{"issue":"7","key":"e_1_2_8_17_1","first-page":"513","article-title":"Sublingual Misoprostol versus Foley catheter for cervical ripening in women with preeclampsia or gestational hypertension: a randomized control trial","volume":"17","author":"Ayati S","year":"2019","journal-title":"Int J Reprod Biomed"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.15285"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/GRF.0000000000000031"}],"container-title":["International Journal of Gynecology &amp; 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