{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T07:31:42Z","timestamp":1781076702635,"version":"3.54.1"},"reference-count":32,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,11,15]],"date-time":"2022-11-15T00:00:00Z","timestamp":1668470400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To determine the effect of female age on pregnancy outcome after in vitro fertilization\/embryo transfer (IVF\u2010ET).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A prospective study was conducted involving 266 women who had IVF\u2010ET at Nisa Fertility and Genetic Center, Abuja, Nigeria. All eligible consenting women were recruited to the study. The main outcome measure was clinical pregnancy. Data were analyzed using IBM SPSS Statistics version 25. <jats:italic>P<\/jats:italic>\u00a0&lt;\u20090.05 at 95% confidence intervals was taken as significant.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 266 patients were recruited and included in the study; 104 pregnancies were recorded, giving an overall pregnancy rate of 39.1%. The age range of the patient was 26\u201343\u2009years (mean age 33.9\u00a0\u00b1\u20092.41\u2009years) while the mean number of embryo transfers per patient was 2.2. The clinical pregnancy rate for women aged below 30\u2009years was 69.4% while the pregnancy rate for patients aged 30\u201334\u2009years, 35\u201339\u2009years, and 40\u201343\u2009years was 52.6%, 24.7%, and 9.4%, respectively (<jats:italic>P<\/jats:italic>\u00a0&lt;\u20090.0001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The study found that the success rate of IVF\u2010ET decreases significantly in women aged over 34\u2009years. Women should be counseled about the age\u2010related risk of infertility and referred to a fertility center as early as possible.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ijgo.14545","type":"journal-article","created":{"date-parts":[[2022,11,4]],"date-time":"2022-11-04T09:04:05Z","timestamp":1667552645000},"page":"283-288","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Correlation of female age with outcome of <scp>IVF<\/scp> in a low\u2010resource setting"],"prefix":"10.1002","volume":"161","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9819-244X","authenticated-orcid":false,"given":"Francis O.","family":"Adebayo","sequence":"first","affiliation":[{"name":"Invitro Fertilization Unit Nisa Fertility and Genetic Center  Abuja Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nkeiruka","family":"Ameh","sequence":"additional","affiliation":[{"name":"Invitro Fertilization Unit Nisa Fertility and Genetic Center  Abuja Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adebiyi G.","family":"Adesiyun","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Ahmadu Bello University  Zaria Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bissallah A.","family":"Ekele","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology University of Abuja Teaching Hospital  Abuja Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ibrahim","family":"Wada","sequence":"additional","affiliation":[{"name":"Invitro Fertilization Unit Nisa Fertility and Genetic Center  Abuja Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,11,15]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmv016"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0803072"},{"key":"e_1_2_8_4_1","first-page":"159","volume-title":"The Impact of Chronic Medical Disorders on Fertility: Infertility and Assisted Conception in the Tropics","author":"Onohwakpor EA","year":"2015"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/dem431"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1023004503697"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.282.19.1832"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0412.2001.080002169.x"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.3109\/09513599809012843"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(99)00121-1"},{"key":"e_1_2_8_11_1","unstructured":"Third\u2010Party Reproduction: Sperm Egg and Embryo Donation and Surrogacy.American Society For Reproductive Medicine;2018."},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rbmo.2012.02.009"},{"issue":"56","key":"e_1_2_8_13_1","first-page":"1","article-title":"Trends in pregnancies and pregnancy rates by outcome: estimates for the United States 1976\u201096","volume":"21","author":"Ventura SJ","year":"2000","journal-title":"Vital Health Stat"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2016.06.021"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.3390\/endocrines2010002"},{"key":"e_1_2_8_16_1","first-page":"2426","article-title":"Trends and outcomes for donor oocyte cycles in the United States, 2000\u20132010","volume":"310","author":"Kawwass JF","year":"2013","journal-title":"Jama"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rbmo.2009.04.002"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2014.09.015"},{"key":"e_1_2_8_19_1","first-page":"422","volume-title":"Calculation of Required Sample Size. 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