{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T15:13:16Z","timestamp":1747149196752,"version":"3.40.5"},"reference-count":24,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To compare the risk of spontaneous preterm birth (SPTB) before 35\u2009weeks in symptomatic and asymptomatic women with cervical shortening at 16\u201334\u2009weeks under mid\u2010trimester universal screening of cervical length (CL).<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Multicenter retrospective cohort study involving six secondary\/tertiary perinatal centers was planned in 2016. Primary outcomes were SPTB before 35\u2009weeks. In all, 407 women were analyzed using multivariable logistic regression analysis for predicting SPTB before 35\u2009weeks while adjusting for presence\/absence of uterine contraction, gestational weeks, vaginal bleeding, and CL classification (1\u20139, 10\u201314, 15\u201319, and 20\u201324\u2009mm) at admission, the execution of cervical cerclage, and the presence\/absence of past history of preterm delivery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>SPTB before 35\u2009weeks of pregnancy occurred in 14.5%. Presence of uterine contraction was not an independent risk factor for SPTB before 35\u2009weeks (adjusted odds ratio [aOR] 1.22, 95% confidence interval [CI] 0.67\u20132.20). CL of 1\u20139\u2009mm, CL of 10\u201314\u2009mm, and vaginal bleeding at admission were independent risk factors for SPTB before 35\u2009weeks (aOR 5.35, 95% CI 2.11\u201313.6; aOR 2.79, 95% CI 1.12\u20136.98; and aOR 2.37, 95% CI 1.12\u20135.10, respectively).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In women with a cervical shortening at 16\u201334\u2009weeks, presence of uterine contractions at admission may not be an independent risk factor for the occurrence of SPTB before 35\u2009weeks.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ijgo.14578","type":"journal-article","created":{"date-parts":[[2022,11,15]],"date-time":"2022-11-15T07:13:01Z","timestamp":1668496381000},"page":"894-902","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Uterine contraction may not be an independent risk factor for spontaneous preterm birth before 35\u2009weeks in women with cervical shortening"],"prefix":"10.1002","volume":"161","author":[{"given":"Kenji","family":"Horie","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Jichi Medical University School of Medicine  Tochigi Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kayo","family":"Takahashi","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Jichi Medical University School of Medicine  Tochigi Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Makiko","family":"Mieno","sequence":"additional","affiliation":[{"name":"Department of Medical Informatics, Center for Information Jichi Medical University School of Medicine  Tochigi Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shiho","family":"Nagayama","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Jichi Medical University School of Medicine  Tochigi 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