{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T14:24:40Z","timestamp":1760711080933,"version":"3.40.5"},"reference-count":25,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,12,4]],"date-time":"2022-12-04T00:00:00Z","timestamp":1670112000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To explore the association between gestational weight gain (GWG) and gestational diabetes mellitus (GDM) in hepatitis B surface antigen (HBsAg) \u2010positive women using a retrospective cohort study to provide advice on the management of GWG.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Our study included 39\u2009539 pregnant women who gave birth at the Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, China. Patients were divided into two groups: the HBsAg\u2010negative and HBsAg\u2010positive groups, comprising 36\u2009500 and 3039 participants, respectively. We used univariate and multivariable logistic regression analyses to explore the association between GWG and GDM in maternal hepatitis B virus (HBV) carrier women.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Being HBsAg positive and excessive GWG were independent risk factors for GDM. Excessive GWG was associated with a higher risk of GDM in HBsAg\u2010positive women. Among pre\u2010pregnancy women of normal weight, HBsAg\u2010positive women with adequate GWG had a higher risk of GDM than HBsAg\u2010negative women, whereas HBsAg\u2010positive women with inadequate GWG had a lower risk of GDM.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The optimal GWG ranges for pre\u2010pregnancy normal\u2010weight HBsAg\u2010positive pregnancies might be lower than the US Institute of Medicine recommendations. HBsAg\u2010positive women should strictly control GWG to reduce the risk of GDM.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ijgo.14583","type":"journal-article","created":{"date-parts":[[2022,11,18]],"date-time":"2022-11-18T17:33:32Z","timestamp":1668792812000},"page":"903-910","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Reducing the risk of gestational diabetes mellitus in chronic hepatitis B virus carriers via more strict control of gestational weight gain"],"prefix":"10.1002","volume":"161","author":[{"given":"Wanchang","family":"Yin","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology The Third Affiliated Hospital of Guangzhou Medical University  Guangzhou China"},{"name":"Department of Obstetrics Dongguan Maternal and Child Health Care Hospital  Dongguan China"},{"name":"Affiliated Dongguan Maternal &amp; Child Healthcare Hospital, Southern Medical University  Dongguan 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