{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T22:37:32Z","timestamp":1778798252432,"version":"3.51.4"},"reference-count":27,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Postpartum hemorrhage is a major cause of maternal morbidity and mortality, so early identification of patients at risk is crucial. In this study, we aim to assess the risk factors for major transfusion in parturients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A case\u2013control study was conducted between 2011 and 2019. The cases included women who were treated with postpartum major transfusion compared with two control groups, one of which was treated with 1\u20132 packed red blood cells and one of which was not treated with packed red blood cells. Cases were matched with controls based on two variables: multiple pregnancies and previous history of three or more cesarean sections. A multivariable conditional logistic regression model was used to determine the role of the independent risk factors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 187\u2009424 deliveries included in the present study, 246 (0.3%) women were treated with major transfusions. After applying a multivariate analysis, maternal age (odds ratio [OR] 1.07, 95% confidence interval [CI] 0.996\u20131.16), antenatal anemia with hemoglobin less than 10\u00a0g\/dL (OR 12.58, 95% CI 2.86\u201355.25), retained placenta (OR 5.5, 95% CI 2.15\u201313.78), and cesarean delivery (OR 10.12, 95% CI 0.93\u20131.95) remained independent risk factors for major transfusions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>Retained placenta and antenatal anemia (hemoglobin\u2009&lt;\u200910\u00a0g\/dL) are independent risk factors for major transfusion. Of these, anemia was found to be the most significant.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ijgo.14747","type":"journal-article","created":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T17:04:46Z","timestamp":1680368686000},"page":"906-912","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Risk factors for blood component therapy in parturients\u2014Case\u2013control study"],"prefix":"10.1002","volume":"162","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7290-3477","authenticated-orcid":false,"given":"Daniel","family":"Gabbai","sequence":"first","affiliation":[{"name":"Division of Obstetrics and Gynecology Lis Maternity Hospital, Tel Aviv Sourasky Medical Center  Tel Aviv Israel"},{"name":"Sackler Faculty of Medicine Tel Aviv University  Tel Aviv Israel"},{"name":"School of Public Heath Sackler Faculty of Medicine Tel Aviv University  Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ariel","family":"Many","sequence":"additional","affiliation":[{"name":"Sackler Faculty of Medicine Tel Aviv University  Tel Aviv Israel"},{"name":"Division of Obstetrics and Gynecology Maayanei Hayeshuah Medical Center  Bnei Brak Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liat","family":"Lerner\u2010Geva","sequence":"additional","affiliation":[{"name":"Sackler Faculty of Medicine Tel Aviv University  Tel Aviv Israel"},{"name":"School of Public Heath Sackler Faculty of Medicine Tel Aviv University  Tel Aviv Israel"},{"name":"Women and Children's Health Research Unit Gertner Institute  Tel\u2010Hashomer Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emmanuel","family":"Attali","sequence":"additional","affiliation":[{"name":"Division of Obstetrics and Gynecology Lis Maternity Hospital, Tel Aviv Sourasky Medical Center  Tel Aviv Israel"},{"name":"Sackler Faculty of Medicine Tel Aviv University  Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,4]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ogx.0000723728.09046.e3"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.16515"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000000746"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000002351"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2015.02.023"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ogc.2007.06.003"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1080\/14767050500170088"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.15208"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000003574"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000219750.79480.84"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000003606"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2014.01.026"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000000054"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1080\/01443610600955792"},{"issue":"2","key":"e_1_2_8_16_1","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1097\/AOG.0b013e3181954e5b","article-title":"Severe obstetric morbidity in the United States: 1998\u20102005","volume":"113","author":"Meikle SF","year":"2009","journal-title":"Obstet Gynecol"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000004478"},{"issue":"2","key":"e_1_2_8_18_1","first-page":"112","article-title":"Patient blood management in obstetrics: prevention and treatment of postpartum haemorrhage. 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