{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T02:41:27Z","timestamp":1792636887933,"version":"4.5.0"},"reference-count":24,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,5,11]],"date-time":"2023-05-11T00:00:00Z","timestamp":1683763200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To evaluate the association of mode of delivery (MOD) with short\u2010term and neurodevelopmental outcomes at 2\u2009years of corrected age (CA) in periviable singleton infants.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective cohort study of the Taiwan Premature Infant Follow\u2010up Network database between 2010 and 2016 compared non\u2010anomalous singleton deliveries (cesarean delivery [CD] vs vaginal delivery [VD]) between 22 0\/7 and 25 6\/7 gestational weeks. Major morbidities, mortality, and neurodevelopmental outcomes were evaluated at 2\u2010year CA.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The CD and VD groups included 354 and 472 infants, respectively. The intraventricular hemorrhage (IVH) rate was lower in the CD group (54% vs 66%,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.001), but severe IVH differed non\u2010significantly between groups (20% vs 26%,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.057). In the small\u2010for\u2010gestational age subgroup, CD was associated with lower IVH (56% vs 84%, adjusted odds ratio [aOR] 0.17, 95% confidence interval [CI] 0.04\u20130.69) and better survival without neurodevelopmental impairment (29% vs 8%, aOR, 6.64, 95% CI 1.02\u201343.29) after controlling for potential confounders.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The optimal MOD for periviable singleton birth and its impact are unclear. CD in periviable singleton births is associated with a decreased IVH risk, without improvement in severe IVH, mortality, or neurodevelopment at 2\u2010year CA. The small\u2010for\u2010gestational age subgroup may benefit from CD for better survival without neurodevelopmental impairment.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ijgo.14833","type":"journal-article","created":{"date-parts":[[2023,5,12]],"date-time":"2023-05-12T02:24:18Z","timestamp":1683858258000},"page":"307-314","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Association of mode of delivery with short\u2010term and neurodevelopmental outcomes in periviable singleton infants: A nationwide database study"],"prefix":"10.1002","volume":"163","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6695-9447","authenticated-orcid":false,"given":"Yi\u2010Ya","family":"Huang","sequence":"first","affiliation":[{"name":"Department of Pediatrics Hsinchu Municipal MacKay Children's Hospital  Hsinchu 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