{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T19:06:58Z","timestamp":1784747218912,"version":"3.55.0"},"reference-count":20,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2023,10,10]],"date-time":"2023-10-10T00:00:00Z","timestamp":1696896000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>This study was conducted to determine the knowledge, practice, and barriers regarding the use of tranexamic acid (TXA) for the prevention and treatment of postpartum hemorrhage (PPH) among health care providers in Enugu, Nigeria.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A cross\u2010sectional study was conducted among health professionals (doctors, pharmacists, and nurses) in two Nigerian tertiary teaching hospitals (one federal and one state). A total of 220 questionnaires were distributed and 207 were returned (response rate: 94%) and analyzed using SPSS for inferential statistics with a level of significance of <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Only 23.7% of the respondents had good knowledge of TXA use in PPH (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001), and awareness of the recent World Health Organization (WHO) recommendation on the use of TXA for PPH was low (19.8%, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). The majority of the respondents had neither prescribed nor dispensed TXA (30%, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). Very few respondents used TXA for all cases of PPH (16.4%, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). Barriers against its use include nonawareness of the latest WHO recommendation, preference for other uterotonics, and cost of the drug.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>There was poor knowledge of TXA, poor awareness of its recommendation, and low use for PPH among different cadres of health care providers.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ijgo.15176","type":"journal-article","created":{"date-parts":[[2023,10,10]],"date-time":"2023-10-10T09:09:54Z","timestamp":1696928994000},"page":"668-676","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Awareness and use of tranexamic acid in the management of postpartum hemorrhage among health care professionals in Enugu, Nigeria"],"prefix":"10.1002","volume":"164","author":[{"given":"Ogochukwu","family":"Onwujekwe","sequence":"first","affiliation":[{"name":"Department of Pharmacy University of Nigeria Teaching Hospital  Enugu Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8442-4358","authenticated-orcid":false,"given":"Adaobi Uchenna","family":"Mosanya","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacy and Pharmacy Management University of Nigeria  Nsukka Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kingsley","family":"Ekwuazi","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology University of Nigeria Teaching Hospital  Enugu Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chukwuemeka","family":"Iyoke","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology University of Nigeria Teaching Hospital  Enugu Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,10,10]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2214-109X(14)70227-X"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/wmh3.291"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(17)30638-4"},{"key":"e_1_2_11_5_1","unstructured":"World Health Organization.Updated WHO Recommendation on Tranexamic Acid for the Treatment of Postpartum Haemorrhage: Highlights and Key Messages from the World Health Organization's 2017 Global Recommendation.2017."},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2019.06.030"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajogmf.2022.100588"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.4103\/2045-9912.318857"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12630-021-01967-7"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.2450\/2018.0026-18"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-022-06845-1"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajem.2022.03.027"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.56126\/73.2.12"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpa.2022.08.004"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2021.09.025"},{"key":"e_1_2_11_16_1","unstructured":"SmithJR.Medscape. Postpartum Hemorrhage.2022. 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