{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T09:28:42Z","timestamp":1767864522124,"version":"3.49.0"},"reference-count":18,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2023,11,22]],"date-time":"2023-11-22T00:00:00Z","timestamp":1700611200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81902131"],"award-info":[{"award-number":["81902131"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007279","name":"Shanghai Municipal Health Bureau","doi-asserted-by":"publisher","award":["20204Y0404"],"award-info":[{"award-number":["20204Y0404"]}],"id":[{"id":"10.13039\/501100007279","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To assess whether serum inhibin A at 14\u201320\u2009weeks of gestation is associated with the occurrence of pre\u2010eclampsia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective cohort study using propensity score matching was conducted on 11\u2009682 singleton pregnant women with established deliveries at the Obstetrics and Gynecology Hospital of Fudan University between January 2017 and July 2019. We investigated serum inhibin A levels at 14\u201320\u2009weeks of gestation and calculated the relative risk between inhibin A and pre\u2010eclampsia by multifactorial logistic regression analysis. Smoothed, fitted curves were used to observe the effect of inhibin A in relation to the occurrence of pre\u2010eclampsia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The risk of pre\u2010eclampsia occurrence increased with elevated serum inhibin A. After full adjustment for confounders, the risk ratio for pre\u2010eclampsia in the group of pregnant women with high inhibin A was 2.92 (95% confidence interval [CI] 2.08\u20134.11) compared with those with normal inhibin A. The results of sensitivity analysis suggested a consistent effect of inhibin A on the risk of pre\u2010eclampsia in different populations.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Elevated serum inhibin A at 14\u201320\u2009weeks of gestation is associated with pre\u2010eclampsia and may provide an early warning signal for pregnancy outcomes associated with pre\u2010eclampsia.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ijgo.15273","type":"journal-article","created":{"date-parts":[[2023,11,23]],"date-time":"2023-11-23T15:48:18Z","timestamp":1700754498000},"page":"786-791","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Association of serum inhibin a with pre\u2010eclampsia: An observational cohort study with propensity score matching"],"prefix":"10.1002","volume":"165","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4030-0166","authenticated-orcid":false,"given":"Chaoyan","family":"Yue","sequence":"first","affiliation":[{"name":"Obstetrics and Gynecology Hospital of Fudan University  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhiheng","family":"Wang","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology Hospital of Fudan University  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Cao","sequence":"additional","affiliation":[{"name":"Department of Breast Surgery, The International Peace Maternity and Child Health Hospital, School of Medicine Shanghai Jiao Tong University  Shanghai China"},{"name":"Department of Breast Surgery Shanghai Key Laboratory of Embryo Original Diseases  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chunmei","family":"Ying","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology Hospital of Fudan University  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,11,22]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/8.6.529"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000172419.37410.eb"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0303-7207(01)00503-2"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.8800"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1258\/acb.2010.010149"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0232634"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0412.2002.810611.x"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.735"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1447-0756.2010.01513.x"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12884-019-2266-y"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijgo.12142"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cca.2020.10.029"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.preghy.2019.03.005"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(06)68397-9"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clp.2010.12.007"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1080\/10641955.2017.1385794"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000002364"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41440-020-00558-1"}],"container-title":["International Journal of Gynecology &amp; 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