{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T00:40:09Z","timestamp":1773103209894,"version":"3.50.1"},"reference-count":20,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2023,12,26]],"date-time":"2023-12-26T00:00:00Z","timestamp":1703548800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To determine the recurrence rate of epithelial ovarian cancer (EOC) and associated factors in an Ethiopian tertiary setting.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A cross\u2010sectional study was conducted on recurrent ovarian cancer at St. Paul's College Millennium Medical College (Ethiopia). Data were collected through chart review using a structured questionnaire. SPSS version 26 was used to analyze the data. Descriptive analysis, bivariate, and multivariate regression analysis were performed as appropriate. Percentages, frequencies, odds ratio with 95% confidence interval (CI) were used to present the results' significance.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 202 patients with EOC were reviewed. The recurrence rate of ovarian cancer (OC) among these patients was 86.1% (a total of 173 patients developed recurrent disease). The commonest site of recurrence was the pelvis (89.1%, 180\/202) and the majority of patients with recurrence were platinum sensitive, accounting for 63.8% (129\/202) of cases. Age \u226540\u2009years (adjusted odds ratio [AOR], 23.3, CI: 4.3\u201331.5), macroscopic residual disease (AOR, 5.2, CI: 1.96\u201317.68), and FIGO Stage III\/IV (AOR, 22.11, CI: 8.3\u201339.13) were associated with recurrence.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The recurrence rate of OC in this study was higher than previous reports. Advanced age at first presentation, extent of residual disease after surgery, and FIGO Stage III and IV disease were associated with disease recurrence.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ijgo.15316","type":"journal-article","created":{"date-parts":[[2023,12,26]],"date-time":"2023-12-26T09:39:10Z","timestamp":1703583550000},"page":"685-690","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Recurrent ovarian cancer in Africa: Rate and associated factors at a gynecologic oncology treatment center in Ethiopia\u2014A\u00a0cross\u2010sectional study"],"prefix":"10.1002","volume":"165","author":[{"given":"Legesse","family":"Demissie","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology St. Paul's Hospital Millennium Medical College  Addis Ababa Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Malede","family":"Birara","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology St. Paul's Hospital Millennium Medical College  Addis Ababa Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lemi Belay","family":"Tolu","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology St. Paul's Hospital Millennium Medical College  Addis Ababa Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5812-0804","authenticated-orcid":false,"given":"Abraham Fessehaye","family":"Sium","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology St. Paul's Hospital Millennium Medical College  Addis Ababa Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,12,26]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijgo.12622"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.20892\/j.issn.2095-3941.2016.0084"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.canep.2018.01.008"},{"issue":"11","key":"e_1_2_10_5_1","first-page":"937","article-title":"Diagnosis and management of ovarian cancer","volume":"93","author":"Doubeni CA","year":"2016","journal-title":"Am Fam Physician"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdw311"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12522-016-0239-7"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rbmo.2014.02.010"},{"issue":"2","key":"e_1_2_10_9_1","article-title":"Surgical cytoreduction for recurrent epithelial ovarian cancer","volume":"2013","author":"Al Rawahi T","year":"2013","journal-title":"Cochrane Database Syst Rev"},{"issue":"6","key":"e_1_2_10_10_1","article-title":"Cytoreductive surgery plus chemotherapy versus chemotherapy alone for recurrent epithelial ovarian cancer","volume":"2010","author":"Galaal K","year":"2010","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13048-016-0301-4"},{"key":"e_1_2_10_12_1","first-page":"882","article-title":"Practice patterns in post\u2010treatment surveillance in patients with primary epithelial ovarian cancer","volume":"31","author":"Demari J","year":"2020","journal-title":"Int J Gynecol Cancer"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.2147\/CMAR.S217329"},{"issue":"1","key":"e_1_2_10_14_1","first-page":"272","article-title":"Risk predictors of early recurrence in women with epithelial ovarian cancer in Lagos, Nigeria","volume":"36","author":"Okunade KS","year":"2020","journal-title":"Pan Afr Med J"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdx441"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/953509"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1080\/02656736.2018.1423708"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2016.11.019"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.2217\/imt.14.90"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1097\/IGC.0000000000000007"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1177\/030089160909500212"}],"container-title":["International Journal of Gynecology &amp; 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