{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T00:26:13Z","timestamp":1791419173986,"version":"4.3.3"},"reference-count":27,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2023,12,22]],"date-time":"2023-12-22T00:00:00Z","timestamp":1703203200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp; Obste"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>This study aimed to compare the perioperative outcomes of patients who underwent hysterectomy for benign gynecologic diseases using transvaginal natural orifice transluminal endoscopic surgery (vNOTES) or transumbilical laparoendoscopic single\u2010site surgery (TU\u2010LESS).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 314 patients who underwent hysterectomy for benign uterine disease at West China Second University Hospital between October 2018 and December 2021 were enrolled in this retrospective study. vNOTES (<jats:italic>n<\/jats:italic>\u2009=\u2009157) and TU\u2010LESS (<jats:italic>n<\/jats:italic>\u2009=\u2009157) recipients were matched 1:1 in terms of uterine volume. The operation time, blood loss, postoperative decrease in hemoglobin, uterus weight, postoperative hospital stay, postoperative pain score at 12\u2009h, postoperative indwelling catheter time, and other clinical indicators were compared between the two groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>All 314 patients successfully completed the surgery, and the two groups had similar baseline characteristics, with no statistical difference. Regarding intraoperative outcomes, the operation time was shorter in the vNOTES group than in the TU\u2010LESS group (80 vs 100\u2009min, <jats:italic>P<\/jats:italic>\u2009=\u20090.04), and there were no significant differences in intraoperative blood loss, intraoperative blood transfusion rate, postoperative decrease in hemoglobin, or uterine weight. Concerning postoperative outcomes, vNOTES hysterectomy was significantly superior to TU\u2010LESS hysterectomy in terms of the length of hospital stay (3 vs 4\u2009days, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001), visual analog scale score for pain at 12\u2009h after surgery (<jats:italic>P<\/jats:italic>\u2009=\u20090.04), postoperative indwelling catheter time (39.5 vs 64.0\u2009h, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001), and postoperative exhaust time (24.0 vs 42.0\u2009h, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). There were no significant differences in postoperative complications between the two groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>vNOTES and TU\u2010LESS seem safe and feasible for hysterectomy, but vNOTES hysterectomy was more conducive to the postoperative rehabilitation of patients, with less trauma, less pain, and better cosmetic effects than TU\u2010LESS hysterectomy. As an emerging surgical approach, more studies, including large\u2010sample, multicenter, randomized controlled trials, are needed to validate our findings.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ijgo.15323","type":"journal-article","created":{"date-parts":[[2023,12,23]],"date-time":"2023-12-23T07:55:00Z","timestamp":1703318100000},"page":"1151-1157","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Perioperative outcomes of transvaginal natural orifice transluminal endoscopic surgery and transumbilical laparoendoscopic single\u2010site surgery in hysterectomy: A comparative study"],"prefix":"10.1002","volume":"165","author":[{"given":"Wenhan","family":"Yuan","sequence":"first","affiliation":[{"name":"Department of Gynecology and Obstetrics, West China Second University Hospital Sichuan University  Chengdu Sichuan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fan","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, West China Second University Hospital Sichuan University  Chengdu Sichuan China"},{"name":"Key Laboratory of Obstetrics and Gynecologic and Pediatric Diseases and Birth Defects of Ministry of Education, West China Second Hospital Sichuan University  Chengdu Sichuan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Zheng","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, West China Second University Hospital Sichuan University  Chengdu Sichuan China"},{"name":"Key Laboratory of Obstetrics and Gynecologic and Pediatric Diseases and Birth Defects of Ministry of Education, West China Second Hospital Sichuan University  Chengdu Sichuan China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,12,22]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2012.11494.x"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2009.05.020"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/jog.14874"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/jog.14603"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2014.01.005"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2020.11.029"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2016.10.044"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm9123959"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2017.07.026"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/GCO.0000000000000090"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2017.09.062"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-008-0206-4"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2019.04.001"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1136\/ijgc-2019-000356"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2018.12.010"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1080\/01443615.2020.1741523"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.5468\/ogs.2018.61.2.261"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-014-3639-y"},{"issue":"3","key":"e_1_2_8_20_1","first-page":"143","article-title":"Exploring the umbilical and vaginal port during minimally invasive surgery","volume":"18","author":"Tinelli A","year":"2017","journal-title":"J Turk Ger Gynecol Assoc"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.3109\/01913123.2011.553351"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1097\/gme.0b013e31823b8983"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.15504"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2020.06.027"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1080\/08941939.2021.1958111"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1080\/08941939.2021.1927262"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2020.10.003"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1080\/13645706.2021.2025111"}],"container-title":["International Journal of Gynecology &amp; Obstetrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijgo.15323","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,12]],"date-time":"2024-05-12T15:52:04Z","timestamp":1715529124000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/ijgo.15323"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12,22]]},"references-count":27,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2024,6]]}},"alternative-id":["10.1002\/ijgo.15323"],"URL":"https:\/\/doi.org\/10.1002\/ijgo.15323","archive":["Portico"],"relation":{},"ISSN":["0020-7292","1879-3479"],"issn-type":[{"value":"0020-7292","type":"print"},{"value":"1879-3479","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,12,22]]},"assertion":[{"value":"2023-06-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-12-11","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-12-22","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}