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Age\u2010related postoperative cognitive disorders (POCD) and postoperative delirium (POD), two serious consequences that are marked by adverse neuropsychologic alterations after surgery, are particularly dangerous for the elderly. In the context of gynecologic procedures, POCD and POD are examined in this narrative review. The main question is how to limit the rates of POCD and POD in older women undergoing gynecologic procedures by maximizing the risk\u2013benefit balance. Three crucial endpoints are considered: (1) surgical procedures to lower the rates of POCD and POD, (2) anesthetic techniques to lessen the occurrence and (3) the identification of individuals at high risk for post\u2010surgery cognitive impairments. Risks associated with laparoscopic gynecologic procedures include the Trendelenburg posture and CO<jats:sub>2<\/jats:sub> exposure during pneumoperitoneum, despite statistical similarities in POD and POCD frequency between laparoscopic and laparotomy techniques. Numerous risk factors are associated with surgical interventions, such as blood loss, length of operation, and position holding, all of which reduce the chance of complications when they are minimized. In order to emphasize the essential role that anesthesia and surgery play in patient care, anesthesiologists are vital in making sure that anesthesia is given as sparingly and quickly as feasible. In addition, people who are genetically predisposed to POCD may be more susceptible to the disorder. The significance of a thorough strategy combining surgical and anesthetic concerns is highlighted in this article, in order to maximize results for senior patients having gynecologic surgery.<\/jats:p>","DOI":"10.1002\/ijgo.15464","type":"journal-article","created":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T12:41:05Z","timestamp":1711975265000},"page":"954-968","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Postoperative cognitive disorders and delirium in gynecologic surgery: Which surgery and anesthetic techniques to use to reduce the risk?"],"prefix":"10.1002","volume":"166","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5928-3565","authenticated-orcid":false,"given":"Giovanni","family":"Pecorella","sequence":"first","affiliation":[{"name":"Department of Gynecology, Obstetrics and Reproduction Medicine Saarland University  Homburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Filippo","family":"De\u00a0Rosa","sequence":"additional","affiliation":[{"name":"Department of Anesthesia and Intensive Care, and CERICSAL (CEntro di RIcerca Clinico SALentino) \"Veris delli Ponti Hospital\"  Scorrano Lecce Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martina","family":"Licchelli","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, and CERICSAL (CEntro di RIcerca Clinico SALentino) \"Veris delli Ponti Hospital\"  Scorrano Lecce Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaetano","family":"Panese","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, and CERICSAL (CEntro di RIcerca Clinico SALentino) \"Veris delli Ponti Hospital\"  Scorrano Lecce Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e8 Tony","family":"Carugno","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology Department, Minimally Invasive Gynecology Division, Miller School of Medicine University of Miami  Miami Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5420-4277","authenticated-orcid":false,"given":"Andrea","family":"Morciano","sequence":"additional","affiliation":[{"name":"Panico Pelvic Floor Center, Department of Gynecology and Obstetrics, Pia Fondazione \"Card. 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