{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T17:25:55Z","timestamp":1772990755330,"version":"3.50.1"},"reference-count":14,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,4,16]],"date-time":"2024-04-16T00:00:00Z","timestamp":1713225600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2024,4,16]],"date-time":"2024-04-16T00:00:00Z","timestamp":1713225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intl J Gynecology &amp;amp; Obste"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To determine whether adenomyosis is present in the cornual portion of hysterectomies of symptomatic sterilization device users and in patients hysterectomized for different benign causes and who presented with pelvic pain and\/or menstrual alterations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>An observational, analytical, cross\u2010sectional, single\u2010center, retrospective cohort study was conducted in a secondary level hospital. Cohort 1 consisted of women who had Essure\u00ae hysteroscopic sterilization devices inserted between 2009 and 2017, who developed gynecologic symptoms (pelvic pain, heavy menstrual bleeding, and\/or abnormal uterine bleeding) and who underwent a hysterectomy for explantation of the devices. Cohort 2 consisted of women with the same gynecologic symptoms, who underwent a hysterectomy for other benign causes. All surgeries were performed by the gynecology team between 2018 and 2022. A descriptive and comparative analysis of sociodemographic, clinical characteristics, and pathologic findings between cohorts was made.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In total, 96 patients were studied (cohort 1 included 34 women, cohort 2 included 62 women). Pelvic pain was found to be more frequent in the cohort of Essure users (76.47% vs. 50%,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.012), with a ratio of three times higher in this group (odds ratio 3.25, 95% confidence interval 1.27\u20138.28). Adenomyosis was more frequently found in the Essure group, both at corporal and cornual portions, the latter being five times higher in this cohort (relative risk\u2009=\u20095.47; 95% confidence interval 1.17\u201325.64).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The present study may be the first to describe cornual adenomyosis related to Essure devices. These devices may play a role in the development of adenomyosis and, consequently, pelvic pain. However, causality is difficult to establish.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ijgo.15541","type":"journal-article","created":{"date-parts":[[2024,4,16]],"date-time":"2024-04-16T06:29:54Z","timestamp":1713248994000},"page":"185-190","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Cornual adenomyosis in Essure\u00ae device users and in patients hysterectomized for other causes: A retrospective cohort study"],"prefix":"10.1002","volume":"167","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1727-9621","authenticated-orcid":false,"given":"Cristina","family":"S\u00e1nchez\u2010Cuerda","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Infanta Sof\u00eda University Hospital  San Sebasti\u00e1n de los Reyes Madrid Spain"},{"name":"European University Madrid  Villaviciosa de Od\u00f3n Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margarita","family":"Elices","sequence":"additional","affiliation":[{"name":"Department of Anatomy Pathology Infanta Sof\u00eda University Hospital  San Sebasti\u00e1n de los Reyes Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paloma","family":"Lobo","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Infanta Sof\u00eda University Hospital  San Sebasti\u00e1n de los Reyes Madrid Spain"},{"name":"European University Madrid  Villaviciosa de Od\u00f3n Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasmina","family":"Cabrera","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Infanta Sof\u00eda University Hospital  San Sebasti\u00e1n de los Reyes Madrid Spain"},{"name":"European University Madrid  Villaviciosa de Od\u00f3n Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvia","family":"Duch","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Infanta Sof\u00eda University Hospital  San Sebasti\u00e1n de los Reyes Madrid Spain"},{"name":"European University Madrid  Villaviciosa de Od\u00f3n Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alicia","family":"Garc\u00eda","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Infanta Sof\u00eda University Hospital  San Sebasti\u00e1n de los Reyes Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9","family":"Rubio","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Infanta Sof\u00eda University Hospital  San Sebasti\u00e1n de los Reyes Madrid Spain"},{"name":"European University Madrid  Villaviciosa de Od\u00f3n Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julio","family":"\u00c1lvarez","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Infanta Sof\u00eda University Hospital  San Sebasti\u00e1n de los Reyes Madrid Spain"},{"name":"European University Madrid  Villaviciosa de Od\u00f3n Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pilar","family":"\u00c1lvarez","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Infanta Sof\u00eda University Hospital  San Sebasti\u00e1n de los Reyes Madrid Spain"},{"name":"European University Madrid  Villaviciosa de Od\u00f3n Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,4,16]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ogx.0000532201.85041.04"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2013.05.006"},{"key":"e_1_2_9_4_1","unstructured":"FDA Meeting of the Obstetrics and Gynecology Devices Advisory Panel September 24 2015. Maude Database. Accessed May 15 2019.Fdanews.com.https:\/\/www.fdanews.com\/ext\/resources\/files\/2016\/09\/09\u201007\u201016Essure.pdf1517068918."},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2016.08.823"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2022.09.018"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2018.10.009"},{"issue":"2","key":"e_1_2_9_8_1","first-page":"89","article-title":"Epidemiology of adenomyosis","volume":"38","author":"Upson K","year":"2020","journal-title":"Semin Reprod Med"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-014-3437-8"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtemb.2021.126891"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.contraception.2020.04.010"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anndiagpath.2020.151508"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jogoh.2020.101836"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2017.05.015"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.contraception.2016.03.017"}],"container-title":["International Journal of Gynecology &amp; Obstetrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijgo.15541","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ijgo.15541","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijgo.15541","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T12:29:39Z","timestamp":1772972979000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/ijgo.15541"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,16]]},"references-count":14,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,10]]}},"alternative-id":["10.1002\/ijgo.15541"],"URL":"https:\/\/doi.org\/10.1002\/ijgo.15541","archive":["Portico"],"relation":{},"ISSN":["0020-7292","1879-3479"],"issn-type":[{"value":"0020-7292","type":"print"},{"value":"1879-3479","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4,16]]},"assertion":[{"value":"2024-02-29","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-04-02","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-04-16","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}